Milestone Pharmaceuticals Inc. (MIST)

NASDAQ: MIST · USD

$0.77

+0.07 (+10.8%)· Recorded snapshot

Market cap	108M
Revenue (ttm)	2.3M
Net income (ttm)	-84M
EPS (ttm)	-$0.71
Shares out	140.9M
Volume	824,512
Beta	1.01

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 2.3M
Net income (ttm): -84M
EPS (ttm): -$0.71
Market cap: 108M

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Halten

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-10-28 19:55 UTC

Forward P/En/a

P25 n/aP50 n/aP75 n/a

Trailing P/En/a

P25 n/aP50 n/aP75 n/a

ROE-35,522.6

P25 n/aP50 n/aP75 n/a

ROIC-49.3

P25 n/aP50 n/aP75 n/a

Benchmarks · 1M

All MIST indicators

Market & fundamental data

Available fields

195

Groups with data

Currency

USD

Showing 195 of 195 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Amount currency	USD
CIK code	0001408443
Company name	Milestone Pharmaceuticals Inc.
Country	Canada
Country code	US
CUSIP number	59935V107
Earnings date	2026-11-11
Earnings time	bmo
Employees	38
Employees change	5
Employees growth	15.15%
Enterprise value	$79.2M
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2003
Industry	Biotechnology
Is primary listing	Yes
Is SPAC	No
ISIN number	CA59935V1076
Last 10-K release date	2026-03-20
Last earnings date	2026-08-12
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$108M
Market cap category	Micro-Cap
Next earnings date	2026-11-11
Options	Yes
Price	$0.77
Price currency	USD
Sector	Healthcare
SIC code	2834
Stock price date	2026-10-28
Symbol	MIST
Website	https://www.milestonepharma.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings yield	-92.94%
EV/Sales	32.21x
FCF / EV yield	-81.68%
FCF yield	-59.14%
Forward EV/Sales	8.91x
Forward P/S	12.31x
P/B ratio	5.35x
P/S ratio	44.49x
Price / tangible book value	5.72x
Sector forward P/E	23.56x
Sector P/E	50.13x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
Gross margin	98.04%
Operating margin	-3,345.24%
Pretax margin	-3,585.62%
Profit per employee	$-2.2M
Revenue per employee	$61,658
ROA	-42.78%
ROA (5Y)	-37.07%
ROCE	-49.16%
ROE	-35,522.62%
ROE (5Y)	-149.92%
ROIC	-49.31%
SBC / revenue	316.77%

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
EPS growth years	0
Gross profit growth 3Y	-27.39%
Gross profit growth 5Y	-42.16%
Net income growth years	0
Revenue growth (QoQ)	134.87%
Revenue growth 3Y	-26.91%
Revenue growth 5Y	-31.02%
Revenue growth years	0

Financial statements

Income-statement and cash-flow amounts, totals and per share.

Metric	Value
Capital expenditures	$-356,000
Depreciation and amortization	$172,000
EBIT	$-78.4M
EBITDA	$-78.2M
EPS	$-0.71
FCF per share	$-0.44
Financing cash flow	$188.8M
Free cash flow	$-61.6M
Free cash flow minus SBC	$-69.1M
Gross profit	$2.3M
Investing cash flow	$-319,000
Net borrowing	$75M
Net cash flow	$127.2M
Net income	$-84M
Operating cash flow minus SBC	$-68.7M
Operating income	$-78.4M
Revenue	$2.3M
Stock-based compensation	$7.4M

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Altman Z-Score	-3.4
Book value per share	$0.13
Debt / equity	7.79
Interest coverage	-7.25
Long-term assets	$1.3M
Long-term liabilities	$141.2M
Net cash (debt)	$28.8M
Net cash / market cap	27.6%
Net debt / equity	-1.58
Piotroski F-Score	2
Property, plant and equipment	$1.3M
Shareholders' equity	$18.2M
Tangible book value	$18.2M
Tangible book value per share	$0.13
Total assets	$181.6M
Total cash	$170.6M
Total debt	$141.8M
Total liabilities	$163.4M
WACC	7.62%

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Asset turnover	0.02
Current assets	$180.3M
Current liabilities	$22.2M
Current ratio	8.13
Net working capital	$-11.8M
Quick ratio	7.87
Working capital	$158.1M
Working capital turnover	0.02

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback yield / dilution	-77.95%
Dividend yield	0%
Shareholder yield	-77.95%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
150-day SMA	$1.26
1D price change	10.85%
1M price change	-2.99%
1M total return	-2.99%
1W price change	6.44%
1W total return	6.44%
1Y price change	-59.96%
1Y return CAGR	-59.98%
1Y total return	-59.96%
20-day SMA	$0.74
200-day SMA	$1.39
3M price change	-32.32%
3M total return	-32.32%
3Y price change	-66.46%
3Y return CAGR	-30.51%
3Y total return	-66.46%
50-day SMA	$0.90
50-day SMA vs 200-day SMA	50under200
52-week high	$3.06
52-week high date	2025-12-12
52-week low	$0.63
52-week low date	2026-10-26
5Y price change	-86.49%
5Y return CAGR	-32.99%
5Y total return	-86.49%
6M price change	-58.88%
6M total return	-58.88%
All-time high	$27.95
All-time high date	2019-06-28
All-time low	$0.63
All-time low date	2025-04-07
Average true range (ATR)	$0.06
Average volume	951.9K
Beta (1Y)	3.89
Beta (2Y)	3.05
Beta (5Y)	1.01
Change from 52-week high	-74.96%
Change from 52-week low	21.48%
Change from all-time high	-97.26%
Change from all-time low	22.29%
Change from open	9.54%
Day's gap	1.2%
Dollar volume	$631,741
High price	$0.77
Low price	$0.70
Monthly RSI	39.25
Open price	$0.70
Position in 52-week range	99.11%
Premarket change	1.15%
Premarket close	$0.69
Premarket price	$0.70
Premarket volume	133
Previous close	$0.69
Price vs 150-day SMA	-39.4%
Price vs 20-day SMA	3.14%
Price vs 200-day SMA	-44.82%
Price vs 50-day SMA	-15.41%
Relative volume	0.87
RSI	48.09
Sharpe ratio	-0.89
Sharpe ratio (3Y)	-0.02
Sharpe ratio (5Y)	-0.12
Sortino ratio	-1.18
Sortino ratio (3Y)	0.03
Sortino ratio (5Y)	-0.09
Volume	824.5K
Weekly RSI	35.84
YTD price change	-62.14%
YTD total return	-62.14%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	106.2M
Float percentage	75.37%
Shares change (QoQ)	6.45%
Shares change (YoY)	77.95%
Shares held by insiders	0.8%
Shares held by institutions	24.1%
Shares outstanding	140.9M
Short % of float	18.56%
Short % of shares	13.99%
Short ratio	13.2 days

Deeper analysis on MIST

14 sections in the full report · jump straight to what you need

Forecast

Base and Bull forecast paths with report-date return framing.

→

Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

→

Sensitivity

Cost-of-equity and terminal-growth stress table.

→

Risks

Kill scenarios, soft-pass flags, and downside catalysts.

→

Earnings

Next earnings setup and beat / inline / miss thresholds.

→

Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

→

Financials

Revenue, margins, cash flow, and balance-sheet context.

→

Peers

Relative valuation and profitability against the cohort.

→

Moat

Economic-profit evidence and competitive advantage risk.

→

Industry cycle

Sector phase, capital cycle, and secular tailwinds.

→

Frequently asked questions

About this MIST report

Is a complete MIST research report available?

No complete published report is available for Milestone Pharmaceuticals Inc. (MIST) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

Milestone Pharmaceuticals Inc. (MIST)

Price

Financial snapshot

Fair-value bridge

Latest news · MIST

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All MIST indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on MIST

Frequently asked questions