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Prime Medicine, Inc. (PRME)

NASDAQ: PRME · USD

$5.37

+1.02 (+23.4%)· Recorded snapshot

Market cap	955.3M
Revenue (ttm)	4.1M
Net income (ttm)	-187.9M
EPS (ttm)	-$1.09
Shares out	177.9M
Volume	14,611,788
Beta	2.38

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 4.1M
Net income (ttm): -187.9M
EPS (ttm): -$1.09
Market cap: 955.3M

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Halten

Metric	Value
Amount currency	USD
CIK code	0001894562
Company name	Prime Medicine, Inc.
Country	United States
Country code	US
CUSIP number	74168J101
Earnings date	2026-11-10
Earnings time	bmo
Employees	146
Employees change	-68
Employees growth	-31.78%
Enterprise value	$972.8M
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2019
In index	RUSSELL2000
Industry	Biotechnology
IPO date	2022-10-20
Is primary listing	Yes
Is SPAC	No
ISIN number	US74168J1016
Last 10-K release date	2026-03-03
Last earnings date	2026-08-06
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$955.3M
Market cap category	Small-Cap
Next earnings date	2026-11-10
Options	Yes
Price	$5.37
Price currency	USD
Sector	Healthcare
SIC code	2836
Stock price date	2026-10-28
Symbol	PRME
U.S. state	Massachusetts
Website	https://primemedicine.com

Metric

Value

Amount currency

USD

CIK code

0001894562

Company name

Prime Medicine, Inc.

Country

United States

Country code

CUSIP number

74168J101

Earnings date

2026-11-10

Earnings time

bmo

Employees

146

Employees change

-68

Employees growth

-31.78%

Enterprise value

$972.8M

Exchange

NASDAQ

Financial currency

USD

Financial report date

2026-06-30

First seen

2026-05-09

Fiscal year end

December

Founded

2019

In index

RUSSELL2000

Industry

Biotechnology

IPO date

2022-10-20

Is primary listing

Yes

Is SPAC

ISIN number

US74168J1016

Last 10-K release date

2026-03-03

Last earnings date

2026-08-06

Last refreshed

2026-10-28

Last stock split type

Never

Market cap

$955.3M

Market cap category

Small-Cap

Next earnings date

2026-11-10

Options

Yes

Price

$5.37

Price currency

USD

Sector

Healthcare

SIC code

2836

Stock price date

2026-10-28

Symbol

PRME

U.S. state

Massachusetts

Website

https://primemedicine.com

Metric	Value
Earnings yield	-20.21%
EV/Sales	233.59x
FCF / EV yield	-16.49%
FCF yield	-16.79%
Forward EV/Sales	97.71x
Forward P/S	95.92x
P/B ratio	19.37x
P/S ratio	229.31x
Price / tangible book value	23.46x
Sector forward P/E	23.56x
Sector P/E	50.08x

Metric

Value

Earnings yield

-20.21%

EV/Sales

233.59x

FCF / EV yield

-16.49%

FCF yield

-16.79%

Forward EV/Sales

97.71x

Forward P/S

95.92x

P/B ratio

19.37x

P/S ratio

229.31x

Price / tangible book value

23.46x

Sector forward P/E

23.56x

Sector P/E

50.08x

Metric	Value
Operating margin	-4,824.94%
Pretax margin	-4,613.11%
Profit per employee	$-1.3M
Revenue per employee	$27,897
ROA	-46.52%
ROA (5Y)	-37.39%
ROCE	-90.42%
ROE	-373.29%
ROE (5Y)	-107.37%
ROIC	-73.79%
SBC / revenue	657.28%

Metric

Value

Operating margin

-4,824.94%

Pretax margin

-4,613.11%

Profit per employee

$-1.3M

Revenue per employee

$27,897

ROA

-46.52%

ROA (5Y)

-37.39%

ROCE

-90.42%

ROE

-373.29%

ROE (5Y)

-107.37%

ROIC

-73.79%

SBC / revenue

657.28%

Metric	Value
EPS growth quarters	9
EPS growth years	4
Net income growth quarters	2
Net income growth years	0
Revenue growth	-17.9%
Revenue growth (Q)	3.5%
Revenue growth (QoQ)	34.81%
Revenue growth 5Y	-4.8%
Revenue growth quarters	1
Revenue growth years	1

Metric

Value

EPS growth quarters

EPS growth years

Net income growth quarters

Net income growth years

Revenue growth

-17.9%

Revenue growth (Q)

3.5%

Revenue growth (QoQ)

34.81%

Revenue growth 5Y

-4.8%

Revenue growth quarters

Revenue growth years

Metric	Value
Capital expenditures	$-797,000
Depreciation and amortization	$7.4M
EBIT	$-196.5M
EBITDA	$-189.1M
EPS	$-1.09
FCF per share	$-0.88
Financing cash flow	$146.1M
Free cash flow	$-156.8M
Free cash flow minus SBC	$-183.6M
Gross profit	$-142.1M
Investing cash flow	$3.6M
Net cash flow	$-6.4M
Net income	$-187.9M
Operating cash flow minus SBC	$-182.8M
Operating income	$-196.5M
Revenue	$4.1M
Stock-based compensation	$26.8M

Metric

Value

Capital expenditures

$-797,000

Depreciation and amortization

$7.4M

EBIT

$-196.5M

EBITDA

$-189.1M

EPS

$-1.09

FCF per share

$-0.88

Financing cash flow

$146.1M

Free cash flow

$-156.8M

Free cash flow minus SBC

$-183.6M

Gross profit

$-142.1M

Investing cash flow

$3.6M

Net cash flow

$-6.4M

Net income

$-187.9M

Operating cash flow minus SBC

$-182.8M

Operating income

$-196.5M

Revenue

$4.1M

Stock-based compensation

$26.8M

Metric	Value
Altman Z-Score	-5.87
Book value per share	$0.22
Debt / equity	2.83
Long-term assets	$152.2M
Long-term liabilities	$177.5M
Net cash (debt)	$-17.4M
Net cash / market cap	-1.86%
Net debt / equity	0.44
Piotroski F-Score	1
Property, plant and equipment	$137.5M
Shareholders' equity	$39.8M
Tangible book value	$39.8M
Tangible book value per share	$0.22
Total assets	$249M
Total cash	$95.1M
Total debt	$112.5M
Total liabilities	$209.2M
WACC	15.46%

Metric

Value

Altman Z-Score

-5.87

Book value per share

$0.22

Debt / equity

2.83

Long-term assets

$152.2M

Long-term liabilities

$177.5M

Net cash (debt)

$-17.4M

Net cash / market cap

-1.86%

Net debt / equity

0.44

Piotroski F-Score

Property, plant and equipment

$137.5M

Shareholders' equity

$39.8M

Tangible book value

$39.8M

Tangible book value per share

$0.22

Total assets

$249M

Total cash

$95.1M

Total debt

$112.5M

Total liabilities

$209.2M

WACC

15.46%

Metric	Value
Asset turnover	0.02
Current assets	$96.8M
Current liabilities	$31.7M
Current ratio	3.05
Net working capital	$-21M
Quick ratio	3
Working capital	$65.1M
Working capital turnover	0.05

Metric

Value

Asset turnover

0.02

Current assets

$96.8M

Current liabilities

$31.7M

Current ratio

3.05

Net working capital

$-21M

Quick ratio

Working capital

$65.1M

Working capital turnover

0.05

Metric	Value
Buyback yield / dilution	-36.42%
Dividend yield	0%
Shareholder yield	-36.42%

Metric

Value

Buyback yield / dilution

-36.42%

Dividend yield

Shareholder yield

-36.42%

Metric	Value
150-day SMA	$3.37
1D price change	23.45%
1M price change	81.03%
1M total return	81.03%
1W price change	33.93%
1W total return	33.93%
1Y price change	1.94%
1Y return CAGR	1.94%
1Y total return	1.94%
20-day SMA	$3.67
200-day SMA	$3.49
3M price change	74.42%
3M total return	74.42%
3Y price change	-6.08%
3Y return CAGR	-2.07%
3Y total return	-6.08%
50-day SMA	$3.47
50-day SMA vs 200-day SMA	50under200
52-week high	$5.40
52-week high date	2026-10-28
52-week low	$2.67
52-week low date	2026-06-11
6M price change	43.05%
6M total return	43.05%
All-time high	$21.73
All-time high date	2022-11-14
All-time low	$1.11
All-time low date	2025-05-20
Average true range (ATR)	$0.41
Average volume	5.7M
Beta (1Y)	2.16
Beta (2Y)	2.83
Beta (5Y)	2.38
Change from 52-week high	-0.56%
Change from 52-week low	101.12%
Change from all-time high	-75.84%
Change from all-time low	372.97%
Change from open	27.86%
Day's gap	-3.45%
Dollar volume	$78.5M
High price	$5.43
Low price	$4.13
Monthly RSI	52.25
Open price	$4.20
Position in 52-week range	95.38%
Premarket change	-0.23%
Premarket close	$4.35
Premarket price	$4.34
Premarket volume	19.6K
Previous close	$4.35
Price vs 150-day SMA	55.74%
Price vs 20-day SMA	42.93%
Price vs 200-day SMA	50.6%
Price vs 50-day SMA	51.21%
Relative volume	2.54
Return from IPO open	-72.32%
Return from IPO price	-69.12%
RSI	72.33
Sharpe ratio	0.42
Sharpe ratio (3Y)	0.34
Sortino ratio	0.78
Sortino ratio (3Y)	0.61
Volume	14.6M
Weekly RSI	66.19
YTD price change	51.3%
YTD total return	51.3%

Metric

Value

150-day SMA

$3.37

1D price change

23.45%

1M price change

81.03%

1M total return

81.03%

1W price change

33.93%

1W total return

33.93%

1Y price change

1.94%

1Y return CAGR

1.94%

1Y total return

1.94%

20-day SMA

$3.67

200-day SMA

$3.49

3M price change

74.42%

3M total return

74.42%

3Y price change

-6.08%

3Y return CAGR

-2.07%

3Y total return

-6.08%

50-day SMA

$3.47

50-day SMA vs 200-day SMA

50under200

52-week high

$5.40

52-week high date

2026-10-28

52-week low

$2.67

52-week low date

2026-06-11

6M price change

43.05%

6M total return

43.05%

All-time high

$21.73

All-time high date

2022-11-14

All-time low

$1.11

All-time low date

2025-05-20

Average true range (ATR)

$0.41

Average volume

5.7M

Beta (1Y)

2.16

Beta (2Y)

2.83

Beta (5Y)

2.38

Change from 52-week high

-0.56%

Change from 52-week low

101.12%

Change from all-time high

-75.84%

Change from all-time low

372.97%

Change from open

27.86%

Day's gap

-3.45%

Dollar volume

$78.5M

High price

$5.43

Low price

$4.13

Monthly RSI

52.25

Open price

$4.20

Position in 52-week range

95.38%

Premarket change

-0.23%

Premarket close

$4.35

Premarket price

$4.34

Premarket volume

19.6K

Previous close

$4.35

Price vs 150-day SMA

55.74%

Price vs 20-day SMA

42.93%

Price vs 200-day SMA

50.6%

Price vs 50-day SMA

51.21%

Relative volume

2.54

Return from IPO open

-72.32%

Return from IPO price

-69.12%

RSI

72.33

Sharpe ratio

0.42

Sharpe ratio (3Y)

0.34

Sortino ratio

0.78

Sortino ratio (3Y)

0.61

Volume

14.6M

Weekly RSI

66.19

YTD price change

51.3%

YTD total return

51.3%

Metric	Value
Float	112.2M
Float percentage	63.09%
Shares change (QoQ)	0.07%
Shares change (YoY)	36.42%
Shares held by insiders	14.52%
Shares held by institutions	53.72%
Shares outstanding	177.9M
Short % of float	29.28%
Short % of shares	18.48%
Short ratio	10 days

Metric

Value

Float

112.2M

Float percentage

63.09%

Shares change (QoQ)

0.07%

Shares change (YoY)

36.42%

Shares held by insiders

14.52%

Shares held by institutions

53.72%

Shares outstanding

177.9M

Short % of float

29.28%

Short % of shares

18.48%

Short ratio

10 days

Metric	Value
Page views	176

Metric

Value

Page views

176

Prime Medicine, Inc. (PRME)

Price

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Profile and market data

Valuation

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Dividends and buybacks

Performance and technicals

Ownership and float

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Frequently asked questions