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Taysha Gene Therapies, Inc. (TSHA)

NASDAQ: TSHA · USD

$4.24

-0.01 (-0.3%)· Recorded snapshot

Market cap	1.4B
Revenue (ttm)	5.5M
Net income (ttm)	-149.6M
EPS (ttm)	-$0.41
Shares out	325.8M
Volume	2,813,183
Beta	1.17

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 5.5M
Net income (ttm): -149.6M
EPS (ttm): -$0.41
Market cap: 1.4B

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Mantener

Metric	Value
Amount currency	USD
CIK code	0001806310
Company name	Taysha Gene Therapies, Inc.
Country	United States
Country code	US
CUSIP number	877619106
Earnings date	2026-11-10
Earnings time	bmo
Employees	99
Employees change	26
Employees growth	35.62%
Enterprise value	$981.2M
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2019
In index	RUSSELL2000
Industry	Biotechnology
IPO date	2020-09-24
Is primary listing	Yes
Is SPAC	No
ISIN number	US8776191061
Last 10-K release date	2026-03-19
Last earnings date	2026-08-11
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$1.4B
Market cap category	Small-Cap
Next earnings date	2026-11-10
Options	Yes
Price	$4.24
Price currency	USD
Sector	Healthcare
SIC code	2836
Stock price date	2026-10-28
Symbol	TSHA
U.S. state	Texas
Website	https://www.tayshagtx.com

Metric

Value

Amount currency

USD

CIK code

0001806310

Company name

Taysha Gene Therapies, Inc.

Country

United States

Country code

CUSIP number

877619106

Earnings date

2026-11-10

Earnings time

bmo

Employees

Employees change

Employees growth

35.62%

Enterprise value

$981.2M

Exchange

NASDAQ

Financial currency

USD

Financial report date

2026-06-30

First seen

2026-05-09

Fiscal year end

December

Founded

2019

In index

RUSSELL2000

Industry

Biotechnology

IPO date

2020-09-24

Is primary listing

Yes

Is SPAC

ISIN number

US8776191061

Last 10-K release date

2026-03-19

Last earnings date

2026-08-11

Last refreshed

2026-10-28

Last stock split type

Never

Market cap

$1.4B

Market cap category

Small-Cap

Next earnings date

2026-11-10

Options

Yes

Price

$4.24

Price currency

USD

Sector

Healthcare

SIC code

2836

Stock price date

2026-10-28

Symbol

TSHA

U.S. state

Texas

Website

https://www.tayshagtx.com

Metric	Value
Earnings yield	-9.77%
EV/Sales	177.11x
FCF / EV yield	-13.65%
FCF yield	-9.68%
Forward EV/Sales	311.54x
Forward P/S	439.4x
P/B ratio	3.57x
P/S ratio	249.8x
Price / tangible book value	3.54x
Sector forward P/E	23.56x
Sector P/E	50.08x

Metric

Value

Earnings yield

-9.77%

EV/Sales

177.11x

FCF / EV yield

-13.65%

FCF yield

-9.68%

Forward EV/Sales

311.54x

Forward P/S

439.4x

P/B ratio

3.57x

P/S ratio

249.8x

Price / tangible book value

3.54x

Sector forward P/E

23.56x

Sector P/E

50.08x

Metric	Value
Gross margin	100%
Operating margin	-2,792.32%
Pretax margin	-2,728.04%
Profit per employee	$-1.5M
Revenue per employee	$55,404
ROA	-23.82%
ROA (5Y)	-36.37%
ROCE	-34.46%
ROE	-47.05%
ROE (5Y)	-185.96%
ROIC	-25.44%
SBC / revenue	331.29%

Metric

Value

Gross margin

100%

Operating margin

-2,792.32%

Pretax margin

-2,728.04%

Profit per employee

$-1.5M

Revenue per employee

$55,404

ROA

-23.82%

ROA (5Y)

-36.37%

ROCE

-34.46%

ROE

-47.05%

ROE (5Y)

-185.96%

ROIC

-25.44%

SBC / revenue

331.29%

Metric	Value
EPS growth years	4
Gross profit growth	-32.27%
Gross profit growth 3Y	-17.03%
Net income growth years	0
Revenue growth	-32.27%
Revenue growth 3Y	-17.03%
Revenue growth years	1

Metric

Value

EPS growth years

Gross profit growth

-32.27%

Gross profit growth 3Y

-17.03%

Net income growth years

Revenue growth

-32.27%

Revenue growth 3Y

-17.03%

Revenue growth years

Metric	Value
Capital expenditures	$-381,000
Depreciation and amortization	$1.2M
EBIT	$-153.2M
EBITDA	$-152M
EPS	$-0.41
FCF per share	$-0.41
Financing cash flow	$275.7M
Free cash flow	$-132.6M
Free cash flow minus SBC	$-150.7M
Gross profit	$5.5M
Investing cash flow	$-3.3M
Net borrowing	$9.2M
Net cash flow	$140.2M
Net income	$-149.6M
Operating cash flow minus SBC	$-150.4M
Operating income	$-153.2M
Revenue	$5.5M
Stock-based compensation	$18.2M

Metric

Value

Capital expenditures

$-381,000

Depreciation and amortization

$1.2M

EBIT

$-153.2M

EBITDA

$-152M

EPS

$-0.41

FCF per share

$-0.41

Financing cash flow

$275.7M

Free cash flow

$-132.6M

Free cash flow minus SBC

$-150.7M

Gross profit

$5.5M

Investing cash flow

$-3.3M

Net borrowing

$9.2M

Net cash flow

$140.2M

Net income

$-149.6M

Operating cash flow minus SBC

$-150.4M

Operating income

$-153.2M

Revenue

$5.5M

Stock-based compensation

$18.2M

Metric	Value
Altman Z-Score	6.81
Book value per share	$1.19
Debt / equity	0.15
Interest coverage	-3,646.64
Long-term assets	$9M
Long-term liabilities	$57.2M
Net cash (debt)	$398.7M
Net cash / market cap	29.1%
Net cash growth	57.59%
Net debt / equity	-1.03
Piotroski F-Score	2
Property, plant and equipment	$8.7M
Shareholders' equity	$387.3M
Tangible book value	$387.3M
Tangible book value per share	$1.19
Total assets	$470.4M
Total cash	$455.4M
Total debt	$56.7M
Total liabilities	$83.2M
WACC	10.27%

Metric

Value

Altman Z-Score

6.81

Book value per share

$1.19

Debt / equity

0.15

Interest coverage

-3,646.64

Long-term assets

$9M

Long-term liabilities

$57.2M

Net cash (debt)

$398.7M

Net cash / market cap

29.1%

Net cash growth

57.59%

Net debt / equity

-1.03

Piotroski F-Score

Property, plant and equipment

$8.7M

Shareholders' equity

$387.3M

Tangible book value

$387.3M

Tangible book value per share

$1.19

Total assets

$470.4M

Total cash

$455.4M

Total debt

$56.7M

Total liabilities

$83.2M

WACC

10.27%

Metric	Value
Asset turnover	0.01
Current assets	$461.4M
Current liabilities	$26M
Current ratio	17.76
Net working capital	$-18.8M
Quick ratio	17.53
Working capital	$435.5M
Working capital turnover	0.02

Metric

Value

Asset turnover

0.01

Current assets

$461.4M

Current liabilities

$26M

Current ratio

17.76

Net working capital

$-18.8M

Quick ratio

17.53

Working capital

$435.5M

Working capital turnover

0.02

Metric	Value
Buyback yield / dilution	-31.09%
Dividend yield	0%
Shareholder yield	-31.09%

Metric

Value

Buyback yield / dilution

-31.09%

Dividend yield

Shareholder yield

-31.09%

Metric	Value
150-day SMA	$5.57
1D price change	-0.35%
1M price change	-9.21%
1M total return	-9.21%
1W price change	3.16%
1W total return	3.16%
1Y price change	-13.11%
1Y return CAGR	-13.12%
1Y total return	-13.11%
20-day SMA	$4.14
200-day SMA	$5.33
3M price change	-23.47%
3M total return	-23.47%
3Y price change	91.42%
3Y return CAGR	24.16%
3Y total return	91.42%
50-day SMA	$4.91
50-day SMA vs 200-day SMA	50under200
52-week high	$7.30
52-week high date	2026-05-06
52-week low	$3.46
52-week low date	2026-10-14
5Y price change	-73.78%
5Y return CAGR	-23.49%
5Y total return	-73.78%
6M price change	-34.37%
6M total return	-34.37%
All-time high	$33.35
All-time high date	2021-01-19
All-time low	$0.50
All-time low date	2023-06-26
Average true range (ATR)	$0.26
Average volume	4.2M
Beta (1Y)	3.47
Beta (2Y)	2.74
Beta (5Y)	1.17
Change from 52-week high	-41.99%
Change from 52-week low	22.58%
Change from all-time high	-87.29%
Change from all-time low	748%
Change from open	2.05%
Day's gap	-2.35%
Dollar volume	$11.9M
High price	$4.27
Low price	$4.15
Monthly RSI	48.86
Open price	$4.15
Position in 52-week range	70.83%
Premarket change	-5.65%
Premarket close	$4.25
Premarket price	$4.01
Premarket volume	900
Previous close	$4.25
Price vs 150-day SMA	-23.88%
Price vs 20-day SMA	2.39%
Price vs 200-day SMA	-20.5%
Price vs 50-day SMA	-13.58%
Relative volume	0.66
Return from IPO open	-81.1%
Return from IPO price	-78.98%
RSI	46.69
Sharpe ratio	0.1
Sharpe ratio (3Y)	0.65
Sharpe ratio (5Y)	0.27
Sortino ratio	0.24
Sortino ratio (3Y)	1.15
Sortino ratio (5Y)	0.65
Volume	2.8M
Weekly RSI	41.12
YTD price change	-22.91%
YTD total return	-22.91%

Metric

Value

150-day SMA

$5.57

1D price change

-0.35%

1M price change

-9.21%

1M total return

-9.21%

1W price change

3.16%

1W total return

3.16%

1Y price change

-13.11%

1Y return CAGR

-13.12%

1Y total return

-13.11%

20-day SMA

$4.14

200-day SMA

$5.33

3M price change

-23.47%

3M total return

-23.47%

3Y price change

91.42%

3Y return CAGR

24.16%

3Y total return

91.42%

50-day SMA

$4.91

50-day SMA vs 200-day SMA

50under200

52-week high

$7.30

52-week high date

2026-05-06

52-week low

$3.46

52-week low date

2026-10-14

5Y price change

-73.78%

5Y return CAGR

-23.49%

5Y total return

-73.78%

6M price change

-34.37%

6M total return

-34.37%

All-time high

$33.35

All-time high date

2021-01-19

All-time low

$0.50

All-time low date

2023-06-26

Average true range (ATR)

$0.26

Average volume

4.2M

Beta (1Y)

3.47

Beta (2Y)

2.74

Beta (5Y)

1.17

Change from 52-week high

-41.99%

Change from 52-week low

22.58%

Change from all-time high

-87.29%

Change from all-time low

748%

Change from open

2.05%

Day's gap

-2.35%

Dollar volume

$11.9M

High price

$4.27

Low price

$4.15

Monthly RSI

48.86

Open price

$4.15

Position in 52-week range

70.83%

Premarket change

-5.65%

Premarket close

$4.25

Premarket price

$4.01

Premarket volume

900

Previous close

$4.25

Price vs 150-day SMA

-23.88%

Price vs 20-day SMA

2.39%

Price vs 200-day SMA

-20.5%

Price vs 50-day SMA

-13.58%

Relative volume

0.66

Return from IPO open

-81.1%

Return from IPO price

-78.98%

RSI

46.69

Sharpe ratio

0.1

Sharpe ratio (3Y)

0.65

Sharpe ratio (5Y)

0.27

Sortino ratio

0.24

Sortino ratio (3Y)

1.15

Sortino ratio (5Y)

0.65

Volume

2.8M

Weekly RSI

41.12

YTD price change

-22.91%

YTD total return

-22.91%

Metric	Value
Float	232.6M
Float percentage	71.39%
Shares change (QoQ)	0.66%
Shares change (YoY)	31.09%
Shares held by insiders	8.07%
Shares held by institutions	73.34%
Shares outstanding	325.8M
Short % of float	23.65%
Short % of shares	16.89%
Short ratio	14.3 days

Metric

Value

Float

232.6M

Float percentage

71.39%

Shares change (QoQ)

0.66%

Shares change (YoY)

31.09%

Shares held by insiders

8.07%

Shares held by institutions

73.34%

Shares outstanding

325.8M

Short % of float

23.65%

Short % of shares

16.89%

Short ratio

14.3 days

Taysha Gene Therapies, Inc. (TSHA)

Price

Financial snapshot

Fair-value bridge

Latest news · TSHA

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All TSHA indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on TSHA

Frequently asked questions