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Rhythm Pharmaceuticals, Inc. (RYTM)

NASDAQ: RYTM · USD

$92.0

-0.17 (-0.2%)· Recorded snapshot

Market cap	6.3B
Revenue (ttm)	239.9M
Net income (ttm)	-210.2M
EPS (ttm)	-$3.12
Shares out	68.9M
Volume	400,662
Beta	2.01

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 239.9M
Net income (ttm): -210.2M
EPS (ttm): -$3.12
Market cap: 6.3B

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Mantenere

Metric	Value
Amount currency	USD
CIK code	0001649904
Company name	Rhythm Pharmaceuticals, Inc.
Country	United States
Country code	US
CUSIP number	76243J105
Earnings date	2026-11-03
Earnings time	bmo
Employees	414
Employees change	131
Employees growth	46.29%
Enterprise value	$6.1B
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2008
In index	RUSSELL2000
Industry	Biotechnology
IPO date	2017-10-05
Is primary listing	Yes
Is SPAC	No
ISIN number	US76243J1051
Last 10-K release date	2026-02-26
Last earnings date	2026-08-04
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$6.3B
Market cap category	Mid-Cap
Next earnings date	2026-11-03
Options	Yes
Price	$92.02
Price currency	USD
Sector	Healthcare
SIC code	2834
Stock price date	2026-10-28
Symbol	RYTM
U.S. state	Massachusetts
Website	https://rhythmtx.com

Metric

Value

Amount currency

USD

CIK code

0001649904

Company name

Rhythm Pharmaceuticals, Inc.

Country

United States

Country code

CUSIP number

76243J105

Earnings date

2026-11-03

Earnings time

bmo

Employees

414

Employees change

131

Employees growth

46.29%

Enterprise value

$6.1B

Exchange

NASDAQ

Financial currency

USD

Financial report date

2026-06-30

First seen

2026-05-09

Fiscal year end

December

Founded

2008

In index

RUSSELL2000

Industry

Biotechnology

IPO date

2017-10-05

Is primary listing

Yes

Is SPAC

ISIN number

US76243J1051

Last 10-K release date

2026-02-26

Last earnings date

2026-08-04

Last refreshed

2026-10-28

Last stock split type

Never

Market cap

$6.3B

Market cap category

Mid-Cap

Next earnings date

2026-11-03

Options

Yes

Price

$92.02

Price currency

USD

Sector

Healthcare

SIC code

2834

Stock price date

2026-10-28

Symbol

RYTM

U.S. state

Massachusetts

Website

https://rhythmtx.com

Metric	Value
Earnings yield	-3.39%
EV/Sales	25.44x
FCF / EV yield	-1.74%
FCF yield	-1.68%
Forward EV/Sales	14.73x
Forward P/S	15.27x
P/B ratio	61.6x
P/S ratio	26.36x
Price / tangible book value	64.47x
Sector forward P/E	23.56x
Sector P/E	50.08x

Metric

Value

Earnings yield

-3.39%

EV/Sales

25.44x

FCF / EV yield

-1.74%

FCF yield

-1.68%

Forward EV/Sales

14.73x

Forward P/S

15.27x

P/B ratio

61.6x

P/S ratio

26.36x

Price / tangible book value

64.47x

Sector forward P/E

23.56x

Sector P/E

50.08x

Metric	Value
EBIT margin	-83.62%
EBITDA margin	-83.17%
Gross margin	89%
Operating margin	-83.62%
Pretax margin	-85.14%
Profit margin	-85.59%
Profit per employee	$-507,783
Revenue per employee	$579,512
ROA	-30.96%
ROA (5Y)	-32.44%
ROCE	-63.96%
ROE	-117.04%
ROE (5Y)	-85.68%
ROIC	-43.64%
SBC / revenue	36.36%
Tax / revenue	0.45%

Metric

Value

EBIT margin

-83.62%

EBITDA margin

-83.17%

Gross margin

89%

Operating margin

-83.62%

Pretax margin

-85.14%

Profit margin

-85.59%

Profit per employee

$-507,783

Revenue per employee

$579,512

ROA

-30.96%

ROA (5Y)

-32.44%

ROCE

-63.96%

ROE

-117.04%

ROE (5Y)

-85.68%

ROIC

-43.64%

SBC / revenue

36.36%

Tax / revenue

0.45%

Metric	Value
EPS growth quarters	1
EPS growth years	1
Gross profit growth	53.09%
Gross profit growth (Q)	45.08%
Gross profit growth 3Y	76.88%
Gross profit growth 5Y	317.67%
Net income growth years	1
Revenue growth	53.51%
Revenue growth (Q)	46.91%
Revenue growth (QoQ)	18.54%
Revenue growth 3Y	76.32%
Revenue growth 5Y	278.46%
Revenue growth quarters	18
Revenue growth years	4

Metric

Value

EPS growth quarters

EPS growth years

Gross profit growth

53.09%

Gross profit growth (Q)

45.08%

Gross profit growth 3Y

76.88%

Gross profit growth 5Y

317.67%

Net income growth years

Revenue growth

53.51%

Revenue growth (Q)

46.91%

Revenue growth (QoQ)

18.54%

Revenue growth 3Y

76.32%

Revenue growth 5Y

278.46%

Revenue growth quarters

Revenue growth years

Metric	Value
Capital expenditures	$-953,000
Depreciation and amortization	$1.1M
EBIT	$-200.6M
EBITDA	$-199.6M
EPS	$-3.12
FCF per share	$-1.54
Financing cash flow	$179.8M
Free cash flow	$-106.3M
Free cash flow minus SBC	$-193.5M
Gross profit	$213.5M
Income taxes	$1.1M
Investing cash flow	$-144.9M
Net cash flow	$-69.9M
Net income	$-210.2M
Operating cash flow minus SBC	$-192.6M
Operating income	$-200.6M
Revenue	$239.9M
Stock-based compensation	$87.2M

Metric

Value

Capital expenditures

$-953,000

Depreciation and amortization

$1.1M

EBIT

$-200.6M

EBITDA

$-199.6M

EPS

$-3.12

FCF per share

$-1.54

Financing cash flow

$179.8M

Free cash flow

$-106.3M

Free cash flow minus SBC

$-193.5M

Gross profit

$213.5M

Income taxes

$1.1M

Investing cash flow

$-144.9M

Net cash flow

$-69.9M

Net income

$-210.2M

Operating cash flow minus SBC

$-192.6M

Operating income

$-200.6M

Revenue

$239.9M

Stock-based compensation

$87.2M

Metric	Value
Altman Z-Score	12.89
Book value per share	$1.50
Debt / equity	0.51
Interest coverage	-10.86
Long-term assets	$10.7M
Long-term liabilities	$96.4M
Net cash (debt)	$221.1M
Net cash / market cap	3.5%
Net cash growth	24.89%
Net debt / equity	-1.02
Piotroski F-Score	4
Property, plant and equipment	$2.9M
Shareholders' equity	$217.3M
Tangible book value	$98.1M
Tangible book value per share	$1.43
Total assets	$437.3M
Total cash	$330.9M
Total debt	$109.8M
Total liabilities	$220M
WACC	15.26%

Metric

Value

Altman Z-Score

12.89

Book value per share

$1.50

Debt / equity

0.51

Interest coverage

-10.86

Long-term assets

$10.7M

Long-term liabilities

$96.4M

Net cash (debt)

$221.1M

Net cash / market cap

3.5%

Net cash growth

24.89%

Net debt / equity

-1.02

Piotroski F-Score

Property, plant and equipment

$2.9M

Shareholders' equity

$217.3M

Tangible book value

$98.1M

Tangible book value per share

$1.43

Total assets

$437.3M

Total cash

$330.9M

Total debt

$109.8M

Total liabilities

$220M

WACC

15.26%

Metric	Value
Asset turnover	0.59
Current assets	$426.6M
Current liabilities	$123.6M
Current ratio	3.45
Inventory turnover	1.07
Net working capital	$-14.5M
Quick ratio	3
Working capital	$303M
Working capital turnover	0.9

Metric

Value

Asset turnover

0.59

Current assets

$426.6M

Current liabilities

$123.6M

Current ratio

3.45

Inventory turnover

1.07

Net working capital

$-14.5M

Quick ratio

Working capital

$303M

Working capital turnover

0.9

Metric	Value
Buyback yield / dilution	-8.09%
Dividend yield	0%
Shareholder yield	-8.09%

Metric

Value

Buyback yield / dilution

-8.09%

Dividend yield

Shareholder yield

-8.09%

Metric	Value
150-day SMA	$97.03
1D price change	-0.18%
1M price change	-6.92%
1M total return	-6.92%
1W price change	1.81%
1W total return	1.81%
1Y price change	-17.68%
1Y return CAGR	-17.69%
1Y total return	-17.68%
20-day SMA	$89.82
200-day SMA	$97.27
3M price change	-13.47%
3M total return	-13.47%
3Y price change	317.41%
3Y return CAGR	60.99%
3Y total return	317.41%
50-day SMA	$97.96
50-day SMA vs 200-day SMA	50over200
52-week high	$122.20
52-week high date	2025-12-11
52-week low	$74.50
52-week low date	2026-03-30
5Y price change	699.22%
5Y return CAGR	51.55%
5Y total return	699.22%
6M price change	7.78%
6M total return	7.78%
All-time high	$122.20
All-time high date	2025-12-11
All-time low	$3.04
All-time low date	2022-05-20
Average true range (ATR)	$3.27
Average volume	665.8K
Beta (1Y)	1.7
Beta (2Y)	1.76
Beta (5Y)	2.01
Change from 52-week high	-24.7%
Change from 52-week low	23.51%
Change from all-time high	-24.85%
Change from all-time low	2,920.72%
Change from open	0.47%
Day's gap	-0.65%
Dollar volume	$36.9M
High price	$92.64
Low price	$91.27
Monthly RSI	54.94
Open price	$91.58
Position in 52-week range	54.38%
Premarket change	0.47%
Premarket close	$92.18
Premarket price	$92.61
Premarket volume	3K
Previous close	$92.18
Price vs 150-day SMA	-5.36%
Price vs 20-day SMA	2.24%
Price vs 200-day SMA	-5.59%
Price vs 50-day SMA	-6.25%
Relative volume	0.6
RSI	48.45
Sharpe ratio	-0.28
Sharpe ratio (3Y)	1.08
Sharpe ratio (5Y)	0.87
Sortino ratio	-0.28
Sortino ratio (3Y)	1.97
Sortino ratio (5Y)	1.58
Volume	400.7K
Weekly RSI	45.37
YTD price change	-14.21%
YTD total return	-14.21%

Metric

Value

150-day SMA

$97.03

1D price change

-0.18%

1M price change

-6.92%

1M total return

-6.92%

1W price change

1.81%

1W total return

1.81%

1Y price change

-17.68%

1Y return CAGR

-17.69%

1Y total return

-17.68%

20-day SMA

$89.82

200-day SMA

$97.27

3M price change

-13.47%

3M total return

-13.47%

3Y price change

317.41%

3Y return CAGR

60.99%

3Y total return

317.41%

50-day SMA

$97.96

50-day SMA vs 200-day SMA

50over200

52-week high

$122.20

52-week high date

2025-12-11

52-week low

$74.50

52-week low date

2026-03-30

5Y price change

699.22%

5Y return CAGR

51.55%

5Y total return

699.22%

6M price change

7.78%

6M total return

7.78%

All-time high

$122.20

All-time high date

2025-12-11

All-time low

$3.04

All-time low date

2022-05-20

Average true range (ATR)

$3.27

Average volume

665.8K

Beta (1Y)

1.7

Beta (2Y)

1.76

Beta (5Y)

2.01

Change from 52-week high

-24.7%

Change from 52-week low

23.51%

Change from all-time high

-24.85%

Change from all-time low

2,920.72%

Change from open

0.47%

Day's gap

-0.65%

Dollar volume

$36.9M

High price

$92.64

Low price

$91.27

Monthly RSI

54.94

Open price

$91.58

Position in 52-week range

54.38%

Premarket change

0.47%

Premarket close

$92.18

Premarket price

$92.61

Premarket volume

Previous close

$92.18

Price vs 150-day SMA

-5.36%

Price vs 20-day SMA

2.24%

Price vs 200-day SMA

-5.59%

Price vs 50-day SMA

-6.25%

Relative volume

0.6

RSI

48.45

Sharpe ratio

-0.28

Sharpe ratio (3Y)

1.08

Sharpe ratio (5Y)

0.87

Sortino ratio

-0.28

Sortino ratio (3Y)

1.97

Sortino ratio (5Y)

1.58

Volume

400.7K

Weekly RSI

45.37

YTD price change

-14.21%

YTD total return

-14.21%

Metric	Value
Float	56M
Float percentage	81.39%
Shares change (QoQ)	0.91%
Shares change (YoY)	8.09%
Shares held by insiders	0.79%
Shares held by institutions	96.31%
Shares outstanding	68.9M
Short % of float	19.64%
Short % of shares	15.98%
Short ratio	16.3 days

Metric

Value

Float

56M

Float percentage

81.39%

Shares change (QoQ)

0.91%

Shares change (YoY)

8.09%

Shares held by insiders

0.79%

Shares held by institutions

96.31%

Shares outstanding

68.9M

Short % of float

19.64%

Short % of shares

15.98%

Short ratio

16.3 days

Rhythm Pharmaceuticals, Inc. (RYTM)

Price

Financial snapshot

Fair-value bridge

Latest news · RYTM

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All RYTM indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on RYTM

Frequently asked questions