Agios Pharmaceuticals, Inc. (AGIO)

NASDAQ: AGIO · USD

$38.1

+0.08 (+0.2%)· Recorded snapshot

Market cap	2.3B
Revenue (ttm)	98.3M
Net income (ttm)	-411.3M
EPS (ttm)	-$7.01
Shares out	59.7M
Volume	756,500
Beta	0.63

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 98.3M
Net income (ttm): -411.3M
EPS (ttm): -$7.01
Market cap: 2.3B

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Aanhouden

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-10-28 19:55 UTC

Forward P/En/a

P25 n/aP50 n/aP75 n/a

Trailing P/En/a

P25 n/aP50 n/aP75 n/a

ROE-34.3

P25 n/aP50 n/aP75 n/a

ROIC-108.3

P25 n/aP50 n/aP75 n/a

Benchmarks · 1M

All AGIO indicators

Market & fundamental data

Available fields

206

Groups with data

Currency

USD

Showing 206 of 206 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Amount currency	USD
CIK code	0001439222
Company name	Agios Pharmaceuticals, Inc.
Country	United States
Country code	US
CUSIP number	00847X104
Earnings date	2026-11-05
Earnings time	bmo
Employees	540
Employees change	52
Employees growth	10.66%
Enterprise value	$1.3B
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2007
In index	RUSSELL2000
Industry	Biotechnology
IPO date	2013-07-24
Is primary listing	Yes
Is SPAC	No
ISIN number	US00847X1046
Last 10-K release date	2026-02-12
Last earnings date	2026-07-30
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$2.3B
Market cap category	Mid-Cap
Next earnings date	2026-11-05
Options	Yes
Price	$38.11
Price currency	USD
Sector	Healthcare
SIC code	2834
Stock price date	2026-10-28
Symbol	AGIO
U.S. state	Massachusetts
Website	https://www.agios.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings yield	-18.39%
EV/Sales	13.84x
FCF / EV yield	-26.84%
FCF yield	-15.92%
Forward EV/Sales	5.18x
Forward P/S	8.73x
P/B ratio	2.21x
P/S ratio	23.33x
Price / tangible book value	2.24x
Sector forward P/E	23.56x
Sector P/E	50.08x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
Gross margin	-270.79%
Operating margin	-466.78%
Pretax margin	-419.27%
Profit per employee	$-761,641
Revenue per employee	$182,107
ROA	-22.24%
ROA (5Y)	-20.34%
ROCE	-44.21%
ROE	-34.34%
ROE (5Y)	-14.25%
ROIC	-108.33%
ROIC (5Y)	-108.55%
SBC / revenue	58.96%
Tax / revenue	-1.03%

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
EPS growth quarters	1
EPS growth years	0
Net income growth quarters	1
Net income growth years	0
Revenue growth	140.58%
Revenue growth (Q)	259.25%
Revenue growth (QoQ)	115.68%
Revenue growth 10Y	7.01%
Revenue growth 3Y	69.63%
Revenue growth quarters	14
Revenue growth years	3

Financial statements

Income-statement and cash-flow amounts, totals and per share.

Metric	Value
Capital expenditures	$-4.7M
Depreciation and amortization	$5.4M
EBIT	$-459M
EBITDA	$-453.7M
EPS	$-7.01
FCF per share	$-6.12
Financing cash flow	$12.2M
Free cash flow	$-365.3M
Free cash flow minus SBC	$-423.2M
Gross profit	$-266.3M
Income taxes	$-1M
Investing cash flow	$367.2M
Net cash flow	$18.8M
Net income	$-411.3M
Operating cash flow minus SBC	$-418.6M
Operating income	$-459M
Revenue	$98.3M
Stock-based compensation	$58M

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Altman Z-Score	12.47
Book value per share	$17.21
Debt / equity	0.03
Long-term assets	$390.8M
Long-term liabilities	$12.2M
Net cash (debt)	$933.7M
Net cash / market cap	40.69%
Net cash growth	-27.66%
Net debt / equity	-0.91
Piotroski F-Score	3
Property, plant and equipment	$33.8M
Shareholders' equity	$1B
Tangible book value	$1B
Tangible book value per share	$17.21
Total assets	$1.1B
Total cash	$617.6M
Total debt	$31.2M
Total liabilities	$82.4M
WACC	7.61%

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Asset turnover	0.08
Current assets	$717.7M
Current liabilities	$70.2M
Current ratio	10.22
Inventory turnover	11.95
Net working capital	$49.1M
Quick ratio	9.14
Working capital	$647.5M
Working capital turnover	0.12

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback yield / dilution	-0.43%
Dividend yield	0%
Shareholder yield	-0.43%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
10Y price change	-21.22%
10Y return CAGR	-2.36%
10Y total return	-21.22%
150-day SMA	$32.78
1D price change	0.21%
1M price change	16.79%
1M total return	16.79%
1W price change	3.85%
1W total return	3.85%
1Y price change	-11.68%
1Y return CAGR	-11.68%
1Y total return	-11.68%
20-day SMA	$33.71
200-day SMA	$31.64
3M price change	2.92%
3M total return	2.92%
3Y price change	90.54%
3Y return CAGR	23.97%
3Y total return	90.54%
50-day SMA	$33.64
50-day SMA vs 200-day SMA	50over200
52-week high	$46.00
52-week high date	2025-11-18
52-week low	$22.24
52-week low date	2025-11-19
5Y price change	-19.03%
5Y return CAGR	-4.13%
5Y total return	-19.03%
6M price change	55.75%
6M total return	55.75%
All-time high	$138.85
All-time high date	2015-01-15
All-time low	$15.77
All-time low date	2013-11-18
Average true range (ATR)	$1.49
Average volume	1.1M
Beta (1Y)	2
Beta (2Y)	1.83
Beta (5Y)	0.63
Change from 52-week high	-17.15%
Change from 52-week low	71.36%
Change from all-time high	-72.6%
Change from all-time low	141.28%
Change from open	1.93%
Day's gap	-1.68%
Dollar volume	$28.8M
High price	$38.43
Low price	$37.22
Monthly RSI	54.18
Open price	$37.39
Position in 52-week range	73.55%
Premarket change	0%
Premarket close	$38.03
Premarket price	$38.03
Previous close	$38.03
Price vs 150-day SMA	16.08%
Price vs 20-day SMA	12.87%
Price vs 200-day SMA	20.26%
Price vs 50-day SMA	13.1%
Relative volume	0.66
RSI	69.35
Sharpe ratio	0.27
Sharpe ratio (3Y)	0.6
Sharpe ratio (5Y)	0.18
Sortino ratio	0.39
Sortino ratio (3Y)	0.91
Sortino ratio (5Y)	0.35
Volume	756.5K
Weekly RSI	61
YTD price change	39.79%
YTD total return	39.79%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	50M
Float percentage	83.78%
Shares change (QoQ)	1.2%
Shares change (YoY)	0.43%
Shares held by insiders	1.11%
Shares held by institutions	100.12%
Shares outstanding	59.7M
Short % of float	14.03%
Short % of shares	11.75%
Short ratio	7.2 days

Deeper analysis on AGIO

14 sections in the full report · jump straight to what you need

Forecast

Base and Bull forecast paths with report-date return framing.

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Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

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Sensitivity

Cost-of-equity and terminal-growth stress table.

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Risks

Kill scenarios, soft-pass flags, and downside catalysts.

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Earnings

Next earnings setup and beat / inline / miss thresholds.

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Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

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Financials

Revenue, margins, cash flow, and balance-sheet context.

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Peers

Relative valuation and profitability against the cohort.

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Moat

Economic-profit evidence and competitive advantage risk.

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Industry cycle

Sector phase, capital cycle, and secular tailwinds.

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Frequently asked questions

About this AGIO report

Is a complete AGIO research report available?

No complete published report is available for Agios Pharmaceuticals, Inc. (AGIO) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

Agios Pharmaceuticals, Inc. (AGIO)

Price

Financial snapshot

Fair-value bridge

Latest news · AGIO

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All AGIO indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on AGIO

Frequently asked questions