Rhythm Pharmaceuticals, Inc. (RYTM)

NASDAQ: RYTM · USD

$92.0

-0.17 (-0.2%)· Recorded snapshot

Market cap	6.3B
Revenue (ttm)	239.9M
Net income (ttm)	-210.2M
EPS (ttm)	-$3.12
Shares out	68.9M
Volume	400,662
Beta	2.01

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 239.9M
Net income (ttm): -210.2M
EPS (ttm): -$3.12
Market cap: 6.3B

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Trzymaj

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-10-28 19:55 UTC

Forward P/En/a

P25 n/aP50 n/aP75 n/a

Trailing P/En/a

P25 n/aP50 n/aP75 n/a

ROE-117

P25 n/aP50 n/aP75 n/a

ROIC-43.6

P25 n/aP50 n/aP75 n/a

Benchmarks · 1M

All RYTM indicators

Market & fundamental data

Available fields

210

Groups with data

Currency

USD

Showing 210 of 210 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Amount currency	USD
CIK code	0001649904
Company name	Rhythm Pharmaceuticals, Inc.
Country	United States
Country code	US
CUSIP number	76243J105
Earnings date	2026-11-03
Earnings time	bmo
Employees	414
Employees change	131
Employees growth	46.29%
Enterprise value	$6.1B
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2008
In index	RUSSELL2000
Industry	Biotechnology
IPO date	2017-10-05
Is primary listing	Yes
Is SPAC	No
ISIN number	US76243J1051
Last 10-K release date	2026-02-26
Last earnings date	2026-08-04
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$6.3B
Market cap category	Mid-Cap
Next earnings date	2026-11-03
Options	Yes
Price	$92.02
Price currency	USD
Sector	Healthcare
SIC code	2834
Stock price date	2026-10-28
Symbol	RYTM
U.S. state	Massachusetts
Website	https://rhythmtx.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings yield	-3.39%
EV/Sales	25.44x
FCF / EV yield	-1.74%
FCF yield	-1.68%
Forward EV/Sales	14.73x
Forward P/S	15.27x
P/B ratio	61.6x
P/S ratio	26.36x
Price / tangible book value	64.47x
Sector forward P/E	23.56x
Sector P/E	50.08x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
EBIT margin	-83.62%
EBITDA margin	-83.17%
Gross margin	89%
Operating margin	-83.62%
Pretax margin	-85.14%
Profit margin	-85.59%
Profit per employee	$-507,783
Revenue per employee	$579,512
ROA	-30.96%
ROA (5Y)	-32.44%
ROCE	-63.96%
ROE	-117.04%
ROE (5Y)	-85.68%
ROIC	-43.64%
SBC / revenue	36.36%
Tax / revenue	0.45%

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
EPS growth quarters	1
EPS growth years	1
Gross profit growth	53.09%
Gross profit growth (Q)	45.08%
Gross profit growth 3Y	76.88%
Gross profit growth 5Y	317.67%
Net income growth years	1
Revenue growth	53.51%
Revenue growth (Q)	46.91%
Revenue growth (QoQ)	18.54%
Revenue growth 3Y	76.32%
Revenue growth 5Y	278.46%
Revenue growth quarters	18
Revenue growth years	4

Financial statements

Income-statement and cash-flow amounts, totals and per share.

Metric	Value
Capital expenditures	$-953,000
Depreciation and amortization	$1.1M
EBIT	$-200.6M
EBITDA	$-199.6M
EPS	$-3.12
FCF per share	$-1.54
Financing cash flow	$179.8M
Free cash flow	$-106.3M
Free cash flow minus SBC	$-193.5M
Gross profit	$213.5M
Income taxes	$1.1M
Investing cash flow	$-144.9M
Net cash flow	$-69.9M
Net income	$-210.2M
Operating cash flow minus SBC	$-192.6M
Operating income	$-200.6M
Revenue	$239.9M
Stock-based compensation	$87.2M

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Altman Z-Score	12.89
Book value per share	$1.50
Debt / equity	0.51
Interest coverage	-10.86
Long-term assets	$10.7M
Long-term liabilities	$96.4M
Net cash (debt)	$221.1M
Net cash / market cap	3.5%
Net cash growth	24.89%
Net debt / equity	-1.02
Piotroski F-Score	4
Property, plant and equipment	$2.9M
Shareholders' equity	$217.3M
Tangible book value	$98.1M
Tangible book value per share	$1.43
Total assets	$437.3M
Total cash	$330.9M
Total debt	$109.8M
Total liabilities	$220M
WACC	15.26%

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Asset turnover	0.59
Current assets	$426.6M
Current liabilities	$123.6M
Current ratio	3.45
Inventory turnover	1.07
Net working capital	$-14.5M
Quick ratio	3
Working capital	$303M
Working capital turnover	0.9

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback yield / dilution	-8.09%
Dividend yield	0%
Shareholder yield	-8.09%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
150-day SMA	$97.03
1D price change	-0.18%
1M price change	-6.92%
1M total return	-6.92%
1W price change	1.81%
1W total return	1.81%
1Y price change	-17.68%
1Y return CAGR	-17.69%
1Y total return	-17.68%
20-day SMA	$89.82
200-day SMA	$97.27
3M price change	-13.47%
3M total return	-13.47%
3Y price change	317.41%
3Y return CAGR	60.99%
3Y total return	317.41%
50-day SMA	$97.96
50-day SMA vs 200-day SMA	50over200
52-week high	$122.20
52-week high date	2025-12-11
52-week low	$74.50
52-week low date	2026-03-30
5Y price change	699.22%
5Y return CAGR	51.55%
5Y total return	699.22%
6M price change	7.78%
6M total return	7.78%
All-time high	$122.20
All-time high date	2025-12-11
All-time low	$3.04
All-time low date	2022-05-20
Average true range (ATR)	$3.27
Average volume	665.8K
Beta (1Y)	1.7
Beta (2Y)	1.76
Beta (5Y)	2.01
Change from 52-week high	-24.7%
Change from 52-week low	23.51%
Change from all-time high	-24.85%
Change from all-time low	2,920.72%
Change from open	0.47%
Day's gap	-0.65%
Dollar volume	$36.9M
High price	$92.64
Low price	$91.27
Monthly RSI	54.94
Open price	$91.58
Position in 52-week range	54.38%
Premarket change	0.47%
Premarket close	$92.18
Premarket price	$92.61
Premarket volume	3K
Previous close	$92.18
Price vs 150-day SMA	-5.36%
Price vs 20-day SMA	2.24%
Price vs 200-day SMA	-5.59%
Price vs 50-day SMA	-6.25%
Relative volume	0.6
RSI	48.45
Sharpe ratio	-0.28
Sharpe ratio (3Y)	1.08
Sharpe ratio (5Y)	0.87
Sortino ratio	-0.28
Sortino ratio (3Y)	1.97
Sortino ratio (5Y)	1.58
Volume	400.7K
Weekly RSI	45.37
YTD price change	-14.21%
YTD total return	-14.21%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	56M
Float percentage	81.39%
Shares change (QoQ)	0.91%
Shares change (YoY)	8.09%
Shares held by insiders	0.79%
Shares held by institutions	96.31%
Shares outstanding	68.9M
Short % of float	19.64%
Short % of shares	15.98%
Short ratio	16.3 days

Deeper analysis on RYTM

14 sections in the full report · jump straight to what you need

Forecast

Base and Bull forecast paths with report-date return framing.

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Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

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Sensitivity

Cost-of-equity and terminal-growth stress table.

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Risks

Kill scenarios, soft-pass flags, and downside catalysts.

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Earnings

Next earnings setup and beat / inline / miss thresholds.

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Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

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Financials

Revenue, margins, cash flow, and balance-sheet context.

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Peers

Relative valuation and profitability against the cohort.

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Moat

Economic-profit evidence and competitive advantage risk.

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Industry cycle

Sector phase, capital cycle, and secular tailwinds.

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Frequently asked questions

About this RYTM report

Is a complete RYTM research report available?

No complete published report is available for Rhythm Pharmaceuticals, Inc. (RYTM) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

Rhythm Pharmaceuticals, Inc. (RYTM)

Price

Financial snapshot

Fair-value bridge

Latest news · RYTM

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All RYTM indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on RYTM

Frequently asked questions