TYO/2160 (TYO/2160)

Tokyo Stock Exchange: TYO/2160 · JPY

¥3,215

+195.09 (+6.5%)· Recorded snapshot

Market cap	211.7B
Revenue (ttm)	26.5B
Net income (ttm)	-5.3B
EPS (ttm)	-¥96.4
Shares out	65.8M
Volume	2,096,300
Beta	1.19

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 26.5B
Net income (ttm): -5.3B
EPS (ttm): -¥96.4
Market cap: 211.7B

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-10-28 19:55 UTC

Forward P/En/a

P25 n/aP50 n/aP75 n/a

Trailing P/En/a

P25 n/aP50 n/aP75 n/a

ROE-10.3

P25 n/aP50 n/aP75 n/a

ROIC-1.7

P25 n/aP50 n/aP75 n/a

Benchmarks · 1M

S&P 500+0.8%

Nasdaq Composite-1.0%

Dow Jones Industrial Average+1.9%

Russell 2000+0.3%

All TYO/2160 indicators

Market & fundamental data

Available fields

200

Groups with data

Currency

JPY

Showing 200 of 200 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Amount currency	JPY
Country	Japan
Country code	JP
Earnings date	2026-11-13
Employees	990
Employees change	123
Employees growth	14.19%
Enterprise value	JPY 225.6B
Exchange	Tokyo Stock Exchange
Financial currency	JPY
Financial report date	2026-06-30
First seen	2026-05-10
Fiscal year end	December
Founded	2001
Industry	Biotechnology
Is primary listing	Yes
ISIN number	JP3386370005
Last earnings date	2026-08-14
Last refreshed	2026-10-28
Last stock split date	2019-09-02
Last stock split type	Forward
Market cap	JPY 211.7B
Next earnings date	2026-11-13
Price	JPY 3,215.00
Price currency	JPY
Sector	Healthcare
SIC code	2836
Stock price date	2026-10-28
Symbol	tyo/2160
Website	https://www.gnipharma.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Average P/E ratio (10Y)	254.79x
Average P/E ratio (5Y)	159.51x
Earnings yield	-3%
EV/Sales	8.51x
FCF / EV yield	-1.5%
FCF yield	-1.6%
P/B ratio	3.18x
P/S ratio	7.98x
Price / tangible book value	23.16x
Price/EBITDA ratio	484.36x
Sector P/E	23.03x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
EBIT margin	-2.97%
EBITDA margin	1.65%
Gross margin	74.61%
Operating margin	-2.97%
Pretax margin	-12.4%
Profit margin	-20.05%
Profit per employee	JPY -5.4M
Profitable quarters	1
Revenue per employee	JPY 26.8M
ROA	-0.66%
ROA (5Y)	1.99%
ROCE	-1.1%
ROE	-10.3%
ROE (5Y)	2.86%
ROIC	-1.75%
ROIC (5Y)	0.28%
Tax / revenue	7.95%

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
EPS growth quarters	1
EPS growth years	0
Gross profit growth	14.37%
Gross profit growth (Q)	-2.4%
Gross profit growth 3Y	-1.14%
Gross profit growth 5Y	14.02%
Net income growth quarters	1
Net income growth years	0
Revenue growth	9.93%
Revenue growth (Q)	-7.51%
Revenue growth (QoQ)	16.02%
Revenue growth 10Y	37.82%
Revenue growth 3Y	4.33%
Revenue growth 5Y	17.47%
Revenue growth years	1

Financial statements

Income-statement and cash-flow amounts, totals and per share.

Metric	Value
Capital expenditures	JPY -309M
Depreciation and amortization	JPY 1.2B
EBIT	JPY -789M
EBITDA	JPY 437M
EPS	JPY -96.36
FCF per share	JPY -51.52
Financing cash flow	JPY 12.1B
Free cash flow	JPY -3.4B
Gross profit	JPY 19.8B
Income taxes	JPY 2.1B
Investing cash flow	JPY -3.7B
Net borrowing	JPY -126M
Net cash flow	JPY 6.6B
Net income	JPY -5.3B
Operating income	JPY -789M
Revenue	JPY 26.5B

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Altman Z-Score	6.66
Book value per share	JPY 724.37
Debt / EBITDA	11.61
Debt / equity	0.08
Goodwill	JPY 16.6B
Interest coverage	-0.44
Long-term assets	JPY 46.1B
Long-term liabilities	JPY 5.1B
Net cash (debt)	JPY 12.1B
Net cash / market cap	5.71%
Net cash growth	113.53%
Net debt / EBITDA	-27.67
Net debt / equity	-0.18
Piotroski F-Score	4
Property, plant and equipment	JPY 7.6B
Shareholders' equity	JPY 66.5B
Tangible book value	JPY 9.1B
Tangible book value per share	JPY 163.73
Total assets	JPY 81.8B
Total cash	JPY 17.2B
Total debt	JPY 5.1B
Total liabilities	JPY 15.3B
WACC	11.22%

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Asset turnover	0.35
Current assets	JPY 35.6B
Current liabilities	JPY 10.2B
Current ratio	3.49
Inventory turnover	1.79
Net working capital	JPY 10.8B
Quick ratio	2.31
Working capital	JPY 25.4B
Working capital turnover	1.25

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback yield / dilution	-9.9%
Shareholder yield	-9.9%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
10Y price change	467.35%
10Y return CAGR	18.96%
10Y total return	467.35%
150-day SMA	JPY 2,877.16
15Y price change	1,339.55%
15Y return CAGR	19.46%
15Y total return	1,339.55%
1D price change	6.46%
1M price change	-0.92%
1M total return	-0.92%
1W price change	14.01%
1W total return	14.01%
1Y price change	28.86%
1Y return CAGR	28.88%
1Y total return	28.86%
20-day SMA	JPY 3,072.30
200-day SMA	JPY 2,851.81
3M price change	24.85%
3M total return	24.85%
3Y price change	64.87%
3Y return CAGR	18.13%
3Y total return	64.87%
50-day SMA	JPY 2,982.26
50-day SMA vs 200-day SMA	50over200
52-week high	JPY 3,740.00
52-week high date	2026-03-11
52-week low	JPY 2,112.00
52-week low date	2025-12-19
5Y price change	97.6%
5Y return CAGR	14.6%
5Y total return	97.6%
6M price change	3.38%
6M total return	3.38%
All-time high	JPY 4,410.00
All-time high date	2025-05-29
All-time low	JPY 13.33
All-time low date	2009-02-26
Average true range (ATR)	JPY 177.84
Average volume	1.7M
Beta (1Y)	0.23
Beta (2Y)	0.82
Beta (5Y)	1.19
Change from 52-week high	-14.04%
Change from 52-week low	52.23%
Change from all-time high	-27.1%
Change from all-time low	24,013.1%
Change from open	1.74%
Day's gap	4.64%
Dollar volume	JPY 6.7B
High price	JPY 3,325.00
Low price	JPY 3,150.00
Monthly RSI	55.2
Open price	JPY 3,160.00
Position in 52-week range	37.14%
Previous close	JPY 3,020.00
Price vs 150-day SMA	11.74%
Price vs 20-day SMA	4.64%
Price vs 200-day SMA	12.74%
Price vs 50-day SMA	7.8%
Relative volume	1.25
RSI	57.6
Sharpe ratio	0.73
Sharpe ratio (3Y)	0.47
Sharpe ratio (5Y)	0.48
Sortino ratio	1.18
Sortino ratio (3Y)	0.8
Sortino ratio (5Y)	0.84
Volume	2.1M
Weekly RSI	56.2
YTD price change	33.29%
YTD total return	33.29%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	56.5M
Shares change (QoQ)	0.2%
Shares change (YoY)	9.9%
Shares held by insiders	3.57%
Shares held by institutions	11.41%
Shares outstanding	65.8M

Deeper analysis on TYO/2160

14 sections in the full report · jump straight to what you need

Forecast

Base and Bull forecast paths with report-date return framing.

→

Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

→

Sensitivity

Cost-of-equity and terminal-growth stress table.

→

Risks

Kill scenarios, soft-pass flags, and downside catalysts.

→

Earnings

Next earnings setup and beat / inline / miss thresholds.

→

Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

→

Financials

Revenue, margins, cash flow, and balance-sheet context.

→

Peers

Relative valuation and profitability against the cohort.

→

Moat

Economic-profit evidence and competitive advantage risk.

→

Industry cycle

Sector phase, capital cycle, and secular tailwinds.

→

Scorecard

Six-factor overlay and 9-category weighted scorecard.

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Recommendation

Final action, action steps, opportunity, and biggest risk.

→

Perspectives

Growth, value, and income investor reads.

→

Frequently asked questions

About this TYO/2160 report

Is a complete TYO/2160 research report available?

No complete published report is available for tyo/2160 (TYO/2160) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

Market cap

211.7B

Revenue (ttm)

26.5B

Net income (ttm)

-5.3B

EPS (ttm)

-¥96.4

Shares out

65.8M

Volume

2,096,300

Beta

1.19

Metric

Value

Amount currency

JPY

Country

Japan

Country code

Earnings date

2026-11-13

Employees

990

Employees change

123

Employees growth

14.19%

Enterprise value

JPY 225.6B

Exchange

Tokyo Stock Exchange

Financial currency

JPY

Financial report date

2026-06-30

First seen

2026-05-10

Fiscal year end

December

Founded

2001

Industry

Biotechnology

Is primary listing

Yes

ISIN number

JP3386370005

Last earnings date

2026-08-14

Last refreshed

2026-10-28

Last stock split date

2019-09-02

Last stock split type

Forward

Market cap

JPY 211.7B

Next earnings date

2026-11-13

Price

JPY 3,215.00

Price currency

JPY

Sector

Healthcare

SIC code

2836

Stock price date

2026-10-28

Symbol

tyo/2160

Website

https://www.gnipharma.com

Metric

Value

Average P/E ratio (10Y)

254.79x

Average P/E ratio (5Y)

159.51x

Earnings yield

-3%

EV/Sales

8.51x

FCF / EV yield

-1.5%

FCF yield

-1.6%

P/B ratio

3.18x

P/S ratio

7.98x

Price / tangible book value

23.16x

Price/EBITDA ratio

484.36x

Sector P/E

23.03x

Metric

Value

EBIT margin

-2.97%

EBITDA margin

1.65%

Gross margin

74.61%

Operating margin

-2.97%

Pretax margin

-12.4%

Profit margin

-20.05%

Profit per employee

JPY -5.4M

Profitable quarters

Revenue per employee

JPY 26.8M

ROA

-0.66%

ROA (5Y)

1.99%

ROCE

-1.1%

ROE

-10.3%

ROE (5Y)

2.86%

ROIC

-1.75%

ROIC (5Y)

0.28%

Tax / revenue

7.95%

Metric

Value

EPS growth quarters

EPS growth years

Gross profit growth

14.37%

Gross profit growth (Q)

-2.4%

Gross profit growth 3Y

-1.14%

Gross profit growth 5Y

14.02%

Net income growth quarters

Net income growth years

Revenue growth

9.93%

Revenue growth (Q)

-7.51%

Revenue growth (QoQ)

16.02%

Revenue growth 10Y

37.82%

Revenue growth 3Y

4.33%

Revenue growth 5Y

17.47%

Revenue growth years

Metric

Value

Capital expenditures

JPY -309M

Depreciation and amortization

JPY 1.2B

EBIT

JPY -789M

EBITDA

JPY 437M

EPS

JPY -96.36

FCF per share

JPY -51.52

Financing cash flow

JPY 12.1B

Free cash flow

JPY -3.4B

Gross profit

JPY 19.8B

Income taxes

JPY 2.1B

Investing cash flow

JPY -3.7B

Net borrowing

JPY -126M

Net cash flow

JPY 6.6B

Net income

JPY -5.3B

Operating income

JPY -789M

Revenue

JPY 26.5B

Metric

Value

Altman Z-Score

6.66

Book value per share

JPY 724.37

Debt / EBITDA

11.61

Debt / equity

0.08

Goodwill

JPY 16.6B

Interest coverage

-0.44

Long-term assets

JPY 46.1B

Long-term liabilities

JPY 5.1B

Net cash (debt)

JPY 12.1B

Net cash / market cap

5.71%

Net cash growth

113.53%

Net debt / EBITDA

-27.67

Net debt / equity

-0.18

Piotroski F-Score

Property, plant and equipment

JPY 7.6B

Shareholders' equity

JPY 66.5B

Tangible book value

JPY 9.1B

Tangible book value per share

JPY 163.73

Total assets

JPY 81.8B

Total cash

JPY 17.2B

Total debt

JPY 5.1B

Total liabilities

JPY 15.3B

WACC

11.22%

Metric

Value

Asset turnover

0.35

Current assets

JPY 35.6B

Current liabilities

JPY 10.2B

Current ratio

3.49

Inventory turnover

1.79

Net working capital

JPY 10.8B

Quick ratio

2.31

Working capital

JPY 25.4B

Working capital turnover

1.25

Metric

Value

Buyback yield / dilution

-9.9%

Shareholder yield

-9.9%

Metric

Value

10Y price change

467.35%

10Y return CAGR

18.96%

10Y total return

467.35%

150-day SMA

JPY 2,877.16

15Y price change

1,339.55%

15Y return CAGR

19.46%

15Y total return

1,339.55%

1D price change

6.46%

1M price change

-0.92%

1M total return

-0.92%

1W price change

14.01%

1W total return

14.01%

1Y price change

28.86%

1Y return CAGR

28.88%

1Y total return

28.86%

20-day SMA

JPY 3,072.30

200-day SMA

JPY 2,851.81

3M price change

24.85%

3M total return

24.85%

3Y price change

64.87%

3Y return CAGR

18.13%

3Y total return

64.87%

50-day SMA

JPY 2,982.26

50-day SMA vs 200-day SMA

50over200

52-week high

JPY 3,740.00

52-week high date

2026-03-11

52-week low

JPY 2,112.00

52-week low date

2025-12-19

5Y price change

97.6%

5Y return CAGR

14.6%

5Y total return

97.6%

6M price change

3.38%

6M total return

3.38%

All-time high

JPY 4,410.00

All-time high date

2025-05-29

All-time low

JPY 13.33

All-time low date

2009-02-26

Average true range (ATR)

JPY 177.84

Average volume

1.7M

Beta (1Y)

0.23

Beta (2Y)

0.82

Beta (5Y)

1.19

Change from 52-week high

-14.04%

Change from 52-week low

52.23%

Change from all-time high

-27.1%

Change from all-time low

24,013.1%

Change from open

1.74%

Day's gap

4.64%

Dollar volume

JPY 6.7B

High price

JPY 3,325.00

Low price

JPY 3,150.00

Monthly RSI

55.2

Open price

JPY 3,160.00

Position in 52-week range

37.14%

Previous close

JPY 3,020.00

Price vs 150-day SMA

11.74%

Price vs 20-day SMA

4.64%

Price vs 200-day SMA

12.74%

Price vs 50-day SMA

7.8%

Relative volume

1.25

RSI

57.6

Sharpe ratio

0.73

Sharpe ratio (3Y)

0.47

Sharpe ratio (5Y)

0.48

Sortino ratio

1.18

Sortino ratio (3Y)

0.8

Sortino ratio (5Y)

0.84

Volume

2.1M

Weekly RSI

56.2

YTD price change

33.29%

YTD total return

33.29%

Metric

Value

Float

56.5M

Shares change (QoQ)

0.2%

Shares change (YoY)

9.9%

Shares held by insiders

3.57%

Shares held by institutions

11.41%

Shares outstanding

65.8M

TYO/2160 (TYO/2160)

Price

Financial snapshot

Fair-value bridge

Latest news · TYO/2160

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All TYO/2160 indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on TYO/2160

Frequently asked questions

TYO/2160 (TYO/2160)

Price

Financial snapshot

Fair-value bridge

Latest news · TYO/2160

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All TYO/2160 indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on TYO/2160

Frequently asked questions