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Health Care / Biotechnology

VRTX stock hub

Vertex is a highly profitable, mature compounder with a dominant franchise in cystic fibrosis generating massive free cash flow. The next phase of growth relies on successfully commercializing its pipeline, including CASGEVY for sickle cell disease and novel pain treatments.

Fair value midpoint
$574
$428 - $722
Upside to midpoint
+33.6%
Based on latest report
Confidence
88/100
Data quality and model convergence
Market cap
$109.1B
NASDAQ
Our take
Research highlights

What our analysis says

Pulled from the latest published report. The full reasoning lives under /analysis.

Biggest opportunity
Bull case
Bull: Rapid adoption of CASGEVY and successful Phase 3 outcomes in pain management diversify revenue streams and reaccelerate top-line growth, driving multiple expansion.
Biggest risk
CASGEVY Launch Stalls
1-3 Years
Recommended action
Strong Buy
Strong Buy. Vertex offers highly visible base cash flows from its CF monopoly combined with compelling optionality from its non-opioid pain and gene-editing pipelines.
Market data

Live price

Polled client-side every 30 s; the bare-URL shell stays cacheable for a full day.

Current price
VRTX
Source: backend price pulse endpoint
In the news

Latest headlines

Fetched client-side; each row carries the publisher and the read-out date.

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Fetching the latest headlines.
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Calendar

Next earnings

Fetched client-side from the daily earnings-calendar mirror.

Upcoming
DateLoading
Window
EPS estimate
Revenue estimate
Analysis map

Jump into the research surface

These links all point into /analysis/*, so a hub rollback leaves the report reader and legacy redirects live.

Forecast
Targets
Bull, base, and bear cases with expected-return framing.
Valuation
Models
Fair-value bridge, DCF, owner earnings, and peer multiples.
Sensitivity
Grid
Cost-of-equity and terminal-growth stress table.
Risks
Bear case
Kill scenarios, soft-pass flags, and downside catalysts.
Earnings
Decision tree
Next earnings setup and beat / inline / miss thresholds.
Position sizing
Checkpoints
Entry, exit, conviction, and quarterly monitoring rules.
Financials
History
Revenue, margins, cash flow, and balance-sheet context.
Peers
Comps
Relative valuation and profitability against the cohort.
Moat
Durability
Economic-profit evidence and competitive advantage risk.
Industry cycle
Context
Sector phase, capital cycle, and secular tailwinds.
Scorecard
Factors
Six-factor overlay and 9-category weighted scorecard.
Recommendation
Verdict
Final action, action steps, opportunity, and biggest risk.
Perspectives
Lenses
Growth, value, and income investor reads.
Archive
History
Prior monthly reports and rating changes.
Sector context

Where the current metrics sit

Percentiles come from the backend screener cohort cache for the ticker's country and sector.

Forward P/E19.9
P25 n/aP50 n/aP75 n/a
Trailing P/E0
P25 n/aP50 n/aP75 n/a
ROE24.2
P25 n/aP50 n/aP75 n/a
ROIC28.6
P25 n/aP50 n/aP75 n/a
Benchmarks - 1M
S&P 500n/a
Nasdaq Compositen/a
Dow Jones Industrial Averagen/a
Russell 2000n/a
Our take
Fast facts

Decision checkpoints

A compact product layer over the same report payload.

Risk gate
3
Named kill scenarios are reviewed before any bullish rating can stand.
Moat score
9/10
Business quality stays separate from stock attractiveness.
Forward P/E
19.9x
Valuation uses the full report model stack, not a single multiple.
Next action
Strong Buy
Final action steps are kept in the recommendation tab.
Our take
Income

Does VRTX pay a dividend?

Capital-return profile from the screener mirror.

Performance

VRTX stock returns vs the market

Total return (incl. dividends) compared to S&P 500.

1Y total return
-1.1%
S&P 500 1Y: n/a
3Y total return
+23.5%
S&P 500 3Y: n/a
5Y total return
+99.9%
S&P 500 5Y: n/a
10Y total return
+402.5%
S&P 500 10Y: n/a
Ownership

Who owns VRTX?

Insider, institutional, and short-interest positioning.

Institutional ownership
+95.5%
Float: +99.7% of shares outstanding
Insider ownership
+0.2%
Stake held by company insiders. Higher generally signals alignment.
Short interest
+1.7%
3.2 days to cover
Y/Y dilution
-0.1%
Negative means the company is buying back shares.
Technical

VRTX momentum and risk profile

RSI, moving-average stack, beta, and risk-adjusted return.

RSI (14)
45.7
Neutral momentum band
Price vs 200-day MA
-1.2%
50/200-day relationship not available
Beta (5Y)
0.30
Less volatile than the market
Sharpe ratio
0.03
Risk-adjusted return — higher is better; >1.0 is solid.
Peers

VRTX vs. sector cohort

Currency-neutral comparison: P/E, P/S, ROIC, 5Y revenue CAGR, and 1Y total return. Market-cap column appears only when every peer reports in the same currency.

TickerNameMarket capP/EP/SROIC5Y rev CAGR1Y total returnRating
AAPLApple Inc.4.3T35.6x9.5x104.3%+6.8%+50.1%売り
ABNBAirbnb Inc.84.1B34.6x6.7x15.9%+29.9%+14.9%ホールド
ADBEAdobe Inc.102.3B14.8x4.2x63.3%+12.3%-34.3%強い買い
ABBVAbbVie Inc.356.5B99.3x5.7x22.2%+4.6%+10.6%ホールド
ABTAbbott Laboratories146.9B23.6x3.3x9.6%+3.9%-35.8%強い買い
AMGNAmgen Inc.179B23.1x4.8x19.1%+8.1%+24.0%強い買い
Questions

About VRTX

Hub-level FAQ points readers to the deeper analysis pages.

What is the current VRTX stock rating?

Vertex Pharmaceuticals Incorporated is currently shown with Strong Buy in the latest report. The hub links directly to the full analysis surface where the rating, fair-value bridge, risks, and scorecard are documented together.

Where can I read the full VRTX analysis?

The full report lives at /stocks/VRTX/analysis. The bare ticker page is a product hub that summarizes the latest read and sends readers into the relocated analysis tabs without making the analysis surface depend on the hub.

What fair-value range is used for VRTX?

The latest report frames VRTX around $428 to $722. Treat that range as the entry point, then check the valuation, sensitivity, and bear-case tabs before making an investment decision.

How often is the VRTX page updated?

The hub updates with the latest published stock report and live backend market data. The analysis pages remain reachable under /analysis, so a hub rollback does not remove the report reader.

Canonical hub: /ja/stocks/VRTX. Analysis surface: /ja/stocks/VRTX/analysis.