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TMO trades against a final fair-value range of $384.14-$618.78, with the midpoint set by the accepted valuation synthesis rather than earlier draft model outputs. Fair value range: low $384, high $619, with mid-point at $501.
Stock analysis

TMO Thermo Fisher Scientific Inc. fair value $501–$619

TMO
By StockMarketAgent.AI team· supervised by
Analyzed: 2026-05-09Next update: 2026-08-09Methodology v2.4Archetype: Mature compounderNYSE · Health Care
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Last price
$474.46
▲ +26.43 (+5.57%)
Fair value
$501
$501–$619
Rating
Hold
confidence 88/100
Upside
+5.6%
upside to fair value
Margin of Safety
$425.76
buy below · 15%
Market Cap
$176.3B
P/E fwd 17.3

§1 Executive summary

  • Composite fair value $501 with high case $619.
  • Implied upside of 5.6% to fair value.
  • Moat 9/10 · confidence 88/100 · Mature compounder.
  • Trades at a measured discount to fair value with adequate margin of safety.
Fair value
$501
Margin of safety
+5.3%
Confidence
88/100
Moat
9/10

Educational analysis only — not financial advice. Always do your own due diligence.

$474.46Price
FV $500.89
High $618.78

TMO trades against a final fair-value range of $384.14-$618.78, with the midpoint set by the accepted valuation synthesis rather than earlier draft model outputs.

  • High Switching Costs
    High Switching Costs
  • Unmatched Scale
    Unmatched Scale
  • Cycle upside
    Accelerating biopharma R&D spend, robust FDA approvals, and strong academic funding drive demand for tools and bioproduction.

§2 Bear case

A stress test assuming flat organic growth for three years and a terminal multipleTerminal multipleThe exit P/E or EV/EBITDA we apply to the final year of an explicit forecast. Anchored to the business's long-run quality and the prevailing risk-free rate. contraction to 15x yields a downside value near $384. This scenario materializes if biopharma R&D budgets are slashed and pricing power evaporates.

Ways this thesis can break

Prolonged Biopharma Funding Winter

· High

Extended depression in early-stage biotech funding permanently impairs the growth trajectory of the life sciences solutions segment.

FV impact
-25%
Trigger
12-24 months

M&A Engine Stalls Under Debt Load

· Medium

Elevated debt levels ($31B+) and higher interest rates restrict accretive acquisitions, eliminating the historical EPS compounding mechanism.

FV impact
-15%
Trigger
2-3 years

Severe Integration Failure

· Low

A major acquisition fails to deliver projected synergies, destroying ROIC and leading to a significant multiple de-rating.

FV impact
-20%
Trigger
1-2 years
Early-warning signals to monitor
MetricCurrentTrigger threshold
Two consecutive quarters of negative organic revenue growth.MonitorDeterioration versus the report thesis
Gross margin contracting by more than 100 basis points year-over-year.MonitorDeterioration versus the report thesis
Net debt to EBITDA ratio sustaining above 3.5x.MonitorDeterioration versus the report thesis
Free cash flow conversion falling persistently below 100% of net income.MonitorDeterioration versus the report thesis
Management abandoning the long-term mid-single-digit organic growth target.MonitorDeterioration versus the report thesis

§3 Financial history

Income statement — last six periods
Line itemT−0T−1T−2T−3T−4CAGR
Period2021-12-312022-12-312023-12-312024-12-312025-12-31Trend
Revenue$39.21B$44.92B$42.86B$42.88B+2.3%
Gross profit$19.64B$18.97B$17.10B$17.70B-2.6%
Operating income$10.23B$8.51B$7.32B$7.72B-6.8%
Net income$7.73B$6.95B$6.00B$6.34B-4.8%
EPS (diluted)$17.63$15.45$16.53$17.74+0.2%
EBITDA$11.97B$11.94B$11.08B$11.54B-0.9%
R&D$1.41B$1.47B$1.34B$1.39B-0.3%
SG&A$8.01B$8.99B$8.45B$8.60B+1.8%

Quality scores

Piotroski F-score
8 / 9
0–9 quality composite
Altman Z-score
3.82
Bankruptcy risk (>3 safe)
Beneish M-score
-2.58
Earnings manipulation risk
OCF / Net income
1.37×
>1 indicates high earnings quality
Accounting quality gate
Pass
Sector-adjusted gate
ROIC
8.2%
Return on invested capital
§3

Numbers analysis

Individual subscribers — §4 onwards11 more sections

Read the full analysis — 11 more sections.

Competitive moat, industry cycle, peer comparison, intrinsic valuation, sensitivity, scenarios, earnings decision tree, position management, investor perspectives, scorecard, and final recommendation.

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FAQ

TMO — frequently asked questions

  1. Based on our latest independent analysis, TMO looks modestly undervalued. The current price is $474 versus a composite fair-value midpoint of $501 (range $384–$619), which implies roughly 5.6% upside to the midpoint.
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