Shuttle Pharmaceuticals Holdings, Inc. (SHPH)

NASDAQ: SHPH · USD

$5.25

+0.04 (+0.8%)· Recorded snapshot

Market cap	25M
Net income (ttm)	-10.3M
EPS (ttm)	-$20.3
Shares out	4.8M
Volume	16,194
Beta	1.14

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Net income (ttm): -10.3M
EPS (ttm): -$20.3
Market cap: 25M

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Hold

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-10-28 19:55 UTC

Forward P/En/a

P25 13.4P50 20.2P75 35.7

Trailing P/En/a

P25 15.4P50 25.8P75 43.5

ROE-90.1

P25 -113.8P50 -46.5P75 -0.9

ROIC-59.2

P25 -68.5P50 -27.1P75 1.8

Benchmarks · 1M

All SHPH indicators

Market & fundamental data

Available fields

177

Groups with data

Currency

USD

Showing 177 of 177 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Amount currency	USD
CIK code	0001757499
Company name	Shuttle Pharmaceuticals Holdings, Inc.
Country	United States
Country code	US
CUSIP number	825693500
Earnings date	2026-11-12
Employees	2
Employees change	-7
Employees growth	-77.78%
Enterprise value	$25.1M
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2012
Industry	Drug Manufacturers - Specialty & Generic
IPO date	2022-08-31
Is primary listing	Yes
Is SPAC	No
ISIN number	US8256935003
Last 10-K release date	2026-03-31
Last earnings date	2026-09-24
Last refreshed	2026-10-28
Last stock split date	2026-06-11
Last stock split type	Reverse
Market cap	$25M
Market cap category	Nano-Cap
Next earnings date	2026-11-12
Options	No
Price	$5.25
Price currency	USD
Sector	Healthcare
SIC code	2834
Stock price date	2026-10-28
Symbol	SHPH
Tags	pharmaceuticals
U.S. state	Maryland
Website	https://www.shuttlepharma.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings yield	-386.62%
FCF / EV yield	-26.21%
FCF yield	-26.32%
Industry forward P/E	13.87x
Industry P/E	173.94x
P/B ratio	0.27x
Price / tangible book value	2.37x
Sector forward P/E	23.56x
Sector P/E	50.08x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
Profit per employee	$-5.1M
ROA	-49.54%
ROA (5Y)	-99.09%
ROCE	-58.05%
ROE	-90.05%
ROIC	-59.2%

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
EPS growth quarters	2
EPS growth years	3
Net income growth quarters	2
Net income growth years	0
Revenue growth years	0

Financial statements

Income-statement and cash-flow amounts, totals and per share.

Metric	Value
Depreciation and amortization	$1.6M
EBIT	$-11.2M
EBITDA	$-9.7M
EPS	$-20.30
FCF per share	$-1.38
Financing cash flow	$10.4M
Free cash flow	$-6.6M
Free cash flow minus SBC	$-7M
Investing cash flow	$-8.5M
Net borrowing	$4.9M
Net cash flow	$-4.7M
Net income	$-10.3M
Operating cash flow minus SBC	$-7M
Operating income	$-11.2M
Stock-based compensation	$376,575

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Book value per share	$19.16
Debt / equity	0.01
Interest coverage	-227.72
Long-term assets	$22.4M
Long-term liabilities	$148,098
Net cash (debt)	$-104,920
Net cash / market cap	-0.42%
Net debt / equity	0.01
Piotroski F-Score	1
Property, plant and equipment	$82,632
Shareholders' equity	$19.2M
Tangible book value	$10.5M
Tangible book value per share	$10.52
Total assets	$22.8M
Total cash	$90,238
Total debt	$195,158
Total liabilities	$3.6M
WACC	10.59%

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Current assets	$396,353
Current liabilities	$3.5M
Current ratio	0.11
Net working capital	$-3.1M
Quick ratio	0.03
Working capital	$-3.1M

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback yield / dilution	-1,009.12%
Dividend yield	0%
Shareholder yield	-1,009.12%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
150-day SMA	$5.07
1D price change	0.77%
1M price change	36.91%
1M total return	36.91%
1W price change	11.81%
1W total return	11.81%
1Y price change	-82.84%
1Y return CAGR	-82.86%
1Y total return	-82.84%
20-day SMA	$4.90
200-day SMA	$7.15
3M price change	88.01%
3M total return	88.01%
3Y price change	-99.44%
3Y return CAGR	-82.26%
3Y total return	-99.44%
50-day SMA	$4.13
50-day SMA vs 200-day SMA	50under200
52-week high	$44.40
52-week high date	2026-01-20
52-week low	$2.58
52-week low date	2026-07-29
6M price change	-47.71%
6M total return	-47.71%
All-time high	$252,520.00
All-time high date	2022-09-01
All-time low	$2.58
All-time low date	2026-07-29
Average true range (ATR)	$0.46
Average volume	44.2K
Beta (1Y)	3.4
Beta (2Y)	1.51
Beta (5Y)	1.14
Change from 52-week high	-88.18%
Change from 52-week low	103.8%
Change from all-time high	-100%
Change from all-time low	113.12%
Change from open	2.54%
Day's gap	-1.73%
Dollar volume	$85,019
High price	$5.57
Low price	$5.12
Monthly RSI	3.37
Open price	$5.12
Position in 52-week range	28.89%
Premarket change	2.57%
Premarket close	$5.21
Premarket price	$5.34
Previous close	$5.21
Price vs 150-day SMA	8.26%
Price vs 20-day SMA	12.09%
Price vs 200-day SMA	-23.23%
Price vs 50-day SMA	33.06%
Relative volume	0.37
Return from IPO open	-99.99%
Return from IPO price	-35.42%
RSI	63.05
Sharpe ratio	-0.57
Sharpe ratio (3Y)	-1
Sortino ratio	-0.78
Sortino ratio (3Y)	-1.35
Volume	16.2K
Weekly RSI	42.82
YTD price change	-69.5%
YTD total return	-69.5%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	4.8M
Float percentage	99.85%
Shares change (QoQ)	101.76%
Shares change (YoY)	1,009.12%
Shares held by insiders	0.15%
Shares held by institutions	0.75%
Shares outstanding	4.8M
Short % of float	0.66%
Short % of shares	0.66%
Short ratio	0.5 days

Deeper analysis on SHPH

14 sections in the full report · jump straight to what you need

Forecast

Base and Bull forecast paths with report-date return framing.

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Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

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Sensitivity

Cost-of-equity and terminal-growth stress table.

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Risks

Kill scenarios, soft-pass flags, and downside catalysts.

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Earnings

Next earnings setup and beat / inline / miss thresholds.

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Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

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Financials

Revenue, margins, cash flow, and balance-sheet context.

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Peers

Relative valuation and profitability against the cohort.

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Moat

Economic-profit evidence and competitive advantage risk.

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Industry cycle

Sector phase, capital cycle, and secular tailwinds.

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Frequently asked questions

About this SHPH report

Is a complete SHPH research report available?

No complete published report is available for Shuttle Pharmaceuticals Holdings, Inc. (SHPH) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

Shuttle Pharmaceuticals Holdings, Inc. (SHPH)

Price

Financial snapshot

Fair-value bridge

Latest news · SHPH

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All SHPH indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on SHPH

Frequently asked questions