Healthcare / BiotechnologyUpdated 2026-05-10 22:07 UTC

SION stock hub

Sionna Therapeutics, Inc. has a live ticker hub with the latest available market, valuation, profitability, growth, ownership, and risk indicators.

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Fair value midpoint

n/a

Fair value pending

Upside to midpoint

n/a

Based on latest report

Confidence

n/a

Data quality and model convergence

Market cap

NASDAQ

Market data

Live price

Current market quote for this ticker.

Current price

SION

In the news

Latest news · SION

Recent company headlines from major financial publishers.

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Fetching the latest headlines.

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Fetching the latest headlines.

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Fetching the latest headlines.

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector context

Where the current metrics sit

Percentiles come from the backend screener cohort cache for the ticker's country and sector.

Forward P/En/a

P25 12.3P50 18.4P75 33.1

Trailing P/En/a

P25 14.9P50 23.2P75 38.5

ROE-31.8

P25 -105.6P50 -46.5P75 -3.1

ROIC-22.6

P25 -63.1P50 -27.3P75 0.5

Benchmarks - 1M

S&P 500n/a

Nasdaq Compositen/a

Dow Jones Industrial Averagen/a

Russell 2000n/a

Indicator catalog

All SION market and fundamental indicators

A searchable catalog of the available market, valuation, profitability, growth, balance-sheet, ownership, and analyst metrics for this ticker.

Available fields

173

Groups with data

Currency

USD

Showing 173 of 173 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Cik	0002036042
Company name	Sionna Therapeutics, Inc.
Country	United States
Country code	US
Cusip	829401108
Employees	59
Employees Change	18%
Employees Change Percent	43.9
Enterprise value	$1.7B
Exchange	NASDAQ
Financial currency	USD
First seen	2026-05-09
Industry	Biotechnology
IPO Date	2025-02-07
Isin	US8294011080
Last refreshed	2026-05-10
Market cap	$2B
Market cap category	Small-Cap
Price	$44.23
Price currency	USD
Sector	Healthcare
Sic	2834
Symbol	SION
Website	https://www.sionnatx.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings Yield	-3.77%
FCF yield	-3.34%
P/B ratio	6.45x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
Net Income	$-75.3M
Net Income Growth Years	0%
Profit Per Employee	$-1.3M
ROA	-21.74
ROCE	-28.32
ROE	-31.79
ROIC	-22.61

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
Cagr1y	243.69%
EPS Growth Quarters	5
EPS Growth Years	2
Revenue Growth Years	0x

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Assets	$326M
Cash	$235.9M
Current Assets	$241.4M
Current Liabilities	$11.7M
Debt	$8.7M
Debt Equity	$0.03
Equity	$306.8M
Liabilities	$19.1M
Long Term Assets	$84.5M
Long Term Liabilities	$7.4M
Net Cash	$301.6M
Net Cash By Market Cap	$15.11
Net Cash Growth	90.55%
Net Debt Equity	$-0.98
Tangible Book Value	$306.8M
Tangible Book Value Per Share	$6.86

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Current ratio	20.61
Net Working Capital	$-4.9M
Quick ratio	20.14
Working Capital	$229.7M

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback Yield	-935.6%
Dividend Yield	0%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
1Y total return	243.4%
200-day SMA	34.66
50-day SMA	38.7
50-day SMA vs 200-day SMA	50over200
All Time High	46.46
All Time High Change	-4.8%
All Time High Date	2026-04-17
All Time Low	7.26
All Time Low Change	509.65%
All Time Low Date	2025-04-11
ATR	3.01
Beta1y	1.95
Beta2y	1.07
Ch YTD	7.51
High	45.1
High52	46.46
High52 Date	2026-04-17
High52ch	-4.8%
Low	43.36
Low52	11.77
Low52 Date	2025-05-15
Low52ch	275.79%
Ma50ch	14.29%
Premarket Change Percent	1.92
Premarket Price	$44.14
Price vs 200-day SMA	27.6%
RSI	61.57
RSI Monthly	74.99
RSI Weekly	60.96
Sharpe ratio	1.85x
Sortino ratio	3.22
Total Return	-935.6%
Tr YTD	7.51
Tr1m	20.32%
Tr1w	12.98%
Tr3m	22.49%

Analyst estimates

Ratings, targets, revisions, and forward estimate fields.

Metric	Value
Analyst Count	9
Analyst Count Top	5
Analyst Price Target Top	$57.4
Analyst Ratings	Strong Buy
Analyst Ratings Top	Strong Buy
Earnings EPS Estimate	$-0.51
Operating Income	$-89M
Price target	$50.44
Price Target Change	$14.04
Price Target Change Top	$29.78

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	16,494,446%
Float Percent	36.54%
Shares Insiders	1.36%
Shares Institutions	40.15%
Shares Out	45,142,330
Shares Qo Q	0.86%
Shares Yo Y	935.6%
Short Float	23.04%
Short Ratio	9.78
Short Shares	8.42

Other indicators

Additional ticker metrics that do not fit the primary research groupings yet.

Metric	Value
Adjusted FCF	$-78.7M
Average Volume	471,398.45x
Bv Per Share	6.86
CAPEX	$-377,000
Ch1m	20.32
Ch1w	12.98
Ch1y	243.4
Ch3m	22.49
Ch6m	27.43
Change	2.12%
Change From Open	0.68
Close	43.31
Days Gap	1.43
Depreciation Amortization	647,000
Dollar Volume	17,926,994
Earnings Date	2026-05-22
Earnings Time	bmo
EBIT	$-89M
EBITDA	$-88.3M
EPS	$-1.88
F Score	2
FCF	$-66.7M
FCF EV Yield	-3.93x
FCF Per Share	$-1.48
Financing CF	205,710,000
Fiscal Year End	December
Founded	2,019
Investing CF	-118,749,000
Ipr	145.7
Iprfo	76.92
Is Primary Listing	1
Is Spac	No
Last Earnings Date	2026-03-02
Last Report Date	2025-12-31
Last Split Type	Never
Last10k Filing Date	2026-03-02
Ma150	38.64
Ma150ch	14.47%
Ma20	41.47
Ma20ch	6.66%
Net CF	20,664,000
Next Earnings Date	2026-05-22
Open	43.93
Optionable	Yes
Position In Range	50
Post Close	44.23
Postmarket Change Percent	-0.5
Postmarket Price	$44.01
Ppne	9,151,000
Pre Close	43.31
Price Date	2026-05-08
Ptbv Ratio	6.51
Relative Volume	0.86x
Share Based Comp	12,066,000
Tr6m	27.43%
Us State	Massachusetts
Volume	405,313

Fast facts

Decision checkpoints

A compact product layer over the same report payload.

Risk gate

n/a

Named kill scenarios are reviewed before any bullish rating can stand.

Moat score

n/a

Business quality stays separate from stock attractiveness.

Forward P/E

n/a

Valuation uses the full report model stack, not a single multiple.

Next action

Research pending

Final action steps are kept in the recommendation tab.

Income

Does SION pay a dividend?

Capital-return profile for this ticker.

Performance

SION stock returns vs the market

Total return (incl. dividends) compared to S&P 500.

Ownership

Who owns SION?

Insider, institutional, and short-interest positioning.

Institutional ownership

+40.2%

Float: +36.5% of shares outstanding

Insider ownership

+1.4%

Stake held by company insiders. Higher generally signals alignment.

Negative means the company is buying back shares.

Technical

SION momentum and risk profile

RSI, moving-average stack, beta, and risk-adjusted return.

RSI (14)

61.6

Neutral momentum band

Price vs 200-day MA

+27.6%

50/200-day relationship not available

Beta (5Y)

n/a

Sensitivity to the broader market

Sharpe ratio

1.85

Risk-adjusted return — higher is better; >1.0 is solid.

Questions

About SION

Hub-level FAQ points readers to the deeper analysis pages.

What is the current SION stock rating?

Sionna Therapeutics, Inc. is currently shown with the latest rating in the latest report. The hub links directly to the full analysis surface where the rating, fair-value bridge, risks, and scorecard are documented together.

Where can I read the full SION analysis?

The full report lives at /stocks/SION/analysis. The bare ticker page is a product hub that summarizes the latest read and sends readers into the relocated analysis tabs without making the analysis surface depend on the hub.

What fair-value range is used for SION?

The latest report frames SION around the latest fair-value range. Treat that range as the entry point, then check the valuation, sensitivity, and bear-case tabs before making an investment decision.

How often is the SION page updated?

The hub updates with the latest published stock report and live backend market data. The analysis pages remain reachable under /analysis, so a hub rollback does not remove the report reader.