Taysha Gene Therapies, Inc. (TSHA)

NASDAQ: TSHA · USD

$4.24

-0.01 (-0.3%)· Recorded snapshot

Market cap	1.4B
Revenue (ttm)	5.5M
Net income (ttm)	-149.6M
EPS (ttm)	-$0.41
Shares out	325.8M
Volume	2,813,183
Beta	1.17

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 5.5M
Net income (ttm): -149.6M
EPS (ttm): -$0.41
Market cap: 1.4B

Ticker	Name	Market cap	P/E	P/S	ROIC	5Y rev CAGR	1Y total return	Rating
EXAS	Exact Sciences Corp	—	—	—	—	—	—	Hold

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-10-28 19:55 UTC

Forward P/En/a

P25 n/aP50 n/aP75 n/a

Trailing P/En/a

P25 n/aP50 n/aP75 n/a

ROE-47.1

P25 n/aP50 n/aP75 n/a

ROIC-25.4

P25 n/aP50 n/aP75 n/a

Benchmarks · 1M

All TSHA indicators

Market & fundamental data

Available fields

200

Groups with data

Currency

USD

Showing 200 of 200 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Amount currency	USD
CIK code	0001806310
Company name	Taysha Gene Therapies, Inc.
Country	United States
Country code	US
CUSIP number	877619106
Earnings date	2026-11-10
Earnings time	bmo
Employees	99
Employees change	26
Employees growth	35.62%
Enterprise value	$981.2M
Exchange	NASDAQ
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-09
Fiscal year end	December
Founded	2019
In index	RUSSELL2000
Industry	Biotechnology
IPO date	2020-09-24
Is primary listing	Yes
Is SPAC	No
ISIN number	US8776191061
Last 10-K release date	2026-03-19
Last earnings date	2026-08-11
Last refreshed	2026-10-28
Last stock split type	Never
Market cap	$1.4B
Market cap category	Small-Cap
Next earnings date	2026-11-10
Options	Yes
Price	$4.24
Price currency	USD
Sector	Healthcare
SIC code	2836
Stock price date	2026-10-28
Symbol	TSHA
U.S. state	Texas
Website	https://www.tayshagtx.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings yield	-9.77%
EV/Sales	177.11x
FCF / EV yield	-13.65%
FCF yield	-9.68%
Forward EV/Sales	311.54x
Forward P/S	439.4x
P/B ratio	3.57x
P/S ratio	249.8x
Price / tangible book value	3.54x
Sector forward P/E	23.56x
Sector P/E	50.08x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
Gross margin	100%
Operating margin	-2,792.32%
Pretax margin	-2,728.04%
Profit per employee	$-1.5M
Revenue per employee	$55,404
ROA	-23.82%
ROA (5Y)	-36.37%
ROCE	-34.46%
ROE	-47.05%
ROE (5Y)	-185.96%
ROIC	-25.44%
SBC / revenue	331.29%

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
EPS growth years	4
Gross profit growth	-32.27%
Gross profit growth 3Y	-17.03%
Net income growth years	0
Revenue growth	-32.27%
Revenue growth 3Y	-17.03%
Revenue growth years	1

Financial statements

Income-statement and cash-flow amounts, totals and per share.

Metric	Value
Capital expenditures	$-381,000
Depreciation and amortization	$1.2M
EBIT	$-153.2M
EBITDA	$-152M
EPS	$-0.41
FCF per share	$-0.41
Financing cash flow	$275.7M
Free cash flow	$-132.6M
Free cash flow minus SBC	$-150.7M
Gross profit	$5.5M
Investing cash flow	$-3.3M
Net borrowing	$9.2M
Net cash flow	$140.2M
Net income	$-149.6M
Operating cash flow minus SBC	$-150.4M
Operating income	$-153.2M
Revenue	$5.5M
Stock-based compensation	$18.2M

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Altman Z-Score	6.81
Book value per share	$1.19
Debt / equity	0.15
Interest coverage	-3,646.64
Long-term assets	$9M
Long-term liabilities	$57.2M
Net cash (debt)	$398.7M
Net cash / market cap	29.1%
Net cash growth	57.59%
Net debt / equity	-1.03
Piotroski F-Score	2
Property, plant and equipment	$8.7M
Shareholders' equity	$387.3M
Tangible book value	$387.3M
Tangible book value per share	$1.19
Total assets	$470.4M
Total cash	$455.4M
Total debt	$56.7M
Total liabilities	$83.2M
WACC	10.27%

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Asset turnover	0.01
Current assets	$461.4M
Current liabilities	$26M
Current ratio	17.76
Net working capital	$-18.8M
Quick ratio	17.53
Working capital	$435.5M
Working capital turnover	0.02

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback yield / dilution	-31.09%
Dividend yield	0%
Shareholder yield	-31.09%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
150-day SMA	$5.57
1D price change	-0.35%
1M price change	-9.21%
1M total return	-9.21%
1W price change	3.16%
1W total return	3.16%
1Y price change	-13.11%
1Y return CAGR	-13.12%
1Y total return	-13.11%
20-day SMA	$4.14
200-day SMA	$5.33
3M price change	-23.47%
3M total return	-23.47%
3Y price change	91.42%
3Y return CAGR	24.16%
3Y total return	91.42%
50-day SMA	$4.91
50-day SMA vs 200-day SMA	50under200
52-week high	$7.30
52-week high date	2026-05-06
52-week low	$3.46
52-week low date	2026-10-14
5Y price change	-73.78%
5Y return CAGR	-23.49%
5Y total return	-73.78%
6M price change	-34.37%
6M total return	-34.37%
All-time high	$33.35
All-time high date	2021-01-19
All-time low	$0.50
All-time low date	2023-06-26
Average true range (ATR)	$0.26
Average volume	4.2M
Beta (1Y)	3.47
Beta (2Y)	2.74
Beta (5Y)	1.17
Change from 52-week high	-41.99%
Change from 52-week low	22.58%
Change from all-time high	-87.29%
Change from all-time low	748%
Change from open	2.05%
Day's gap	-2.35%
Dollar volume	$11.9M
High price	$4.27
Low price	$4.15
Monthly RSI	48.86
Open price	$4.15
Position in 52-week range	70.83%
Premarket change	-5.65%
Premarket close	$4.25
Premarket price	$4.01
Premarket volume	900
Previous close	$4.25
Price vs 150-day SMA	-23.88%
Price vs 20-day SMA	2.39%
Price vs 200-day SMA	-20.5%
Price vs 50-day SMA	-13.58%
Relative volume	0.66
Return from IPO open	-81.1%
Return from IPO price	-78.98%
RSI	46.69
Sharpe ratio	0.1
Sharpe ratio (3Y)	0.65
Sharpe ratio (5Y)	0.27
Sortino ratio	0.24
Sortino ratio (3Y)	1.15
Sortino ratio (5Y)	0.65
Volume	2.8M
Weekly RSI	41.12
YTD price change	-22.91%
YTD total return	-22.91%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	232.6M
Float percentage	71.39%
Shares change (QoQ)	0.66%
Shares change (YoY)	31.09%
Shares held by insiders	8.07%
Shares held by institutions	73.34%
Shares outstanding	325.8M
Short % of float	23.65%
Short % of shares	16.89%
Short ratio	14.3 days

Deeper analysis on TSHA

14 sections in the full report · jump straight to what you need

Forecast

Base and Bull forecast paths with report-date return framing.

→

Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

→

Sensitivity

Cost-of-equity and terminal-growth stress table.

→

Risks

Kill scenarios, soft-pass flags, and downside catalysts.

→

Earnings

Next earnings setup and beat / inline / miss thresholds.

→

Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

→

Financials

Revenue, margins, cash flow, and balance-sheet context.

→

Peers

Relative valuation and profitability against the cohort.

→

Moat

Economic-profit evidence and competitive advantage risk.

→

Industry cycle

Sector phase, capital cycle, and secular tailwinds.

→

Frequently asked questions

About this TSHA report

Is a complete TSHA research report available?

No complete published report is available for Taysha Gene Therapies, Inc. (TSHA) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

Taysha Gene Therapies, Inc. (TSHA)

Price

Financial snapshot

Fair-value bridge

Latest news · TSHA

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All TSHA indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on TSHA

Frequently asked questions