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LON/0QZU (LON/0QZU)

London Stock Exchange: LON/0QZU · USD

$529

+10.78 (+2.1%)· Recorded snapshot

Market cap	101.5B
Revenue (ttm)	9.5B
Net income (ttm)	3.3B
EPS (ttm)	$12.9
P/E (trailing)	30.8x
P/E (forward)	28.8x
Volume	2,600
Beta	0.28

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 9.5B
Net income (ttm): 3.3B
EPS (ttm): $12.9
P/E (trailing): 30.8x
P/E (forward): 28.8x
Market cap: 101.5B

Metric	Value
Amount currency	GBP
Country	United States
Country code	UK
Earnings date	2026-11-02
Employees	6,400
Employees change	300
Employees growth	4.92%
Enterprise value	$92.7B
Exchange	London Stock Exchange
Financial currency	USD
Financial report date	2026-06-30
First seen	2026-05-10
Fiscal year end	December
Founded	1989
Industry	Biotechnology
Is primary listing	No
ISIN number	US92532F1003
Last earnings date	2026-08-03
Last refreshed	2026-10-28
Market cap	$101.5B
Next earnings date	2026-11-02
Price	$529.10
Price currency	USD
Sector	Healthcare
SIC code	2836
Stock price date	2026-10-28
Symbol	lon/0QZU
Website	https://www.vrtx.com

Metric

Value

Amount currency

GBP

Country

United States

Country code

Earnings date

2026-11-02

Employees

6,400

Employees change

300

Employees growth

4.92%

Enterprise value

$92.7B

Exchange

London Stock Exchange

Financial currency

USD

Financial report date

2026-06-30

First seen

2026-05-10

Fiscal year end

December

Founded

1989

Industry

Biotechnology

Is primary listing

ISIN number

US92532F1003

Last earnings date

2026-08-03

Last refreshed

2026-10-28

Market cap

$101.5B

Next earnings date

2026-11-02

Price

$529.10

Price currency

USD

Sector

Healthcare

SIC code

2836

Stock price date

2026-10-28

Symbol

lon/0QZU

Website

https://www.vrtx.com

Metric	Value
Average P/E ratio (10Y)	50.03x
Average P/E ratio (3Y)	28.04x
Average P/E ratio (5Y)	26.01x
Earnings yield	3.25%
EV/Earnings	27.25x
EV/EBIT	24.52x
EV/EBITDA	22.32x
EV/FCF	31.62x
EV/Sales	9.57x
FCF / EV yield	3.16%
FCF yield	2.88%
Forward P/E	28.82x
Graham number	178.23002
Graham upside	-65.98%
Lynch fair value	$301.53
Lynch upside	-42.44%
P/(FCF - SBC) ratio	42.38x
P/(OCF - SBC) ratio	36.54x
P/B ratio	6.5x
P/E ratio	30.79x
P/FCF ratio	34.69x
P/OCF ratio	30.67x
P/S ratio	10.46x
Price / tangible book value	7.02x
Price/EBITDA ratio	25.82x
Sector forward P/E	14.52x
Sector P/E	22.58x

Metric

Value

Average P/E ratio (10Y)

50.03x

Average P/E ratio (3Y)

28.04x

Average P/E ratio (5Y)

26.01x

Earnings yield

3.25%

EV/Earnings

27.25x

EV/EBIT

24.52x

EV/EBITDA

22.32x

EV/FCF

31.62x

EV/Sales

9.57x

FCF / EV yield

3.16%

FCF yield

2.88%

Forward P/E

28.82x

Graham number

178.23002

Graham upside

-65.98%

Lynch fair value

$301.53

Lynch upside

-42.44%

P/(FCF - SBC) ratio

42.38x

P/(OCF - SBC) ratio

36.54x

P/B ratio

6.5x

P/E ratio

30.79x

P/FCF ratio

34.69x

P/OCF ratio

30.67x

P/S ratio

10.46x

Price / tangible book value

7.02x

Price/EBITDA ratio

25.82x

Sector forward P/E

14.52x

Sector P/E

22.58x

Metric	Value
EBIT margin	39%
EBITDA margin	40.52%
Effective tax rate	16.48%
FCF margin	30.2%
Gross margin	54.96%
Operating margin	39%
Pretax margin	41.9%
Profit margin	35%
Profit per employee	$518,781
Profitable quarters	8
Profitable years	1
Revenue per employee	$1.5M
ROA	11.93%
ROA (5Y)	14.82%
ROCE	20.9%
ROE	23.54%
ROE (5Y)	19%
ROIC	28.8%
ROIC (5Y)	37.75%
SBC / revenue	5.47%
Tax / revenue	6.91%

Metric

Value

EBIT margin

39%

EBITDA margin

40.52%

Effective tax rate

16.48%

FCF margin

30.2%

Gross margin

54.96%

Operating margin

39%

Pretax margin

41.9%

Profit margin

35%

Profit per employee

$518,781

Profitable quarters

Profitable years

Revenue per employee

$1.5M

ROA

11.93%

ROA (5Y)

14.82%

ROCE

20.9%

ROE

23.54%

ROE (5Y)

19%

ROIC

28.8%

ROIC (5Y)

37.75%

SBC / revenue

5.47%

Tax / revenue

6.91%

Metric	Value
EPS growth	22.12%
EPS growth (Q)	8.02%
EPS growth (QoQ)	7.21%
EPS growth 3Y	9.92%
EPS growth 5Y	17.77%
EPS growth quarters	5
EPS growth years	1
FCF growth	8.47%
FCF growth (Q)	9.25%
FCF growth (QoQ)	-21.74%
FCF growth 3Y	-0.71%
FCF growth 5Y	16.39%
Gross profit growth	15.3%
Gross profit growth (Q)	17.23%
Gross profit growth 3Y	8.01%
Gross profit growth 5Y	11.52%
Net income growth	21.1%
Net income growth (Q)	6.48%
Net income growth (QoQ)	6.63%
Net income growth 3Y	9.4%
Net income growth 5Y	17.2%
Net income growth quarters	5
Net income growth years	1
OCF growth	11.61%
OCF growth (Q)	4.87%
OCF growth (QoQ)	-21.2%
OCF growth 3Y	1.81%
OCF growth 5Y	15.15%
Operating income growth	10.85%
Operating income growth (Q)	9.92%
Operating income growth 3Y	3.16%
Operating income growth 5Y	8.75%
Revenue growth	10.23%
Revenue growth (Q)	12.45%
Revenue growth (QoQ)	11.62%
Revenue growth 10Y	23.24%
Revenue growth 3Y	9.81%
Revenue growth 5Y	13.5%
Revenue growth quarters	33
Revenue growth years	11

Metric

Value

EPS growth

22.12%

EPS growth (Q)

8.02%

EPS growth (QoQ)

7.21%

EPS growth 3Y

9.92%

EPS growth 5Y

17.77%

EPS growth quarters

EPS growth years

FCF growth

8.47%

FCF growth (Q)

9.25%

FCF growth (QoQ)

-21.74%

FCF growth 3Y

-0.71%

FCF growth 5Y

16.39%

Gross profit growth

15.3%

Gross profit growth (Q)

17.23%

Gross profit growth 3Y

8.01%

Gross profit growth 5Y

11.52%

Net income growth

21.1%

Net income growth (Q)

6.48%

Net income growth (QoQ)

6.63%

Net income growth 3Y

9.4%

Net income growth 5Y

17.2%

Net income growth quarters

Net income growth years

OCF growth

11.61%

OCF growth (Q)

4.87%

OCF growth (QoQ)

-21.2%

OCF growth 3Y

1.81%

OCF growth 5Y

15.15%

Operating income growth

10.85%

Operating income growth (Q)

9.92%

Operating income growth 3Y

3.16%

Operating income growth 5Y

8.75%

Revenue growth

10.23%

Revenue growth (Q)

12.45%

Revenue growth (QoQ)

11.62%

Revenue growth 10Y

23.24%

Revenue growth 3Y

9.81%

Revenue growth 5Y

13.5%

Revenue growth quarters

Revenue growth years

Metric	Value
Capital expenditures	$-374.4M
Depreciation and amortization	$143.7M
EBIT	$3.7B
EBITDA	$3.8B
EPS	$12.93
Financing cash flow	$-1.7B
Free cash flow	$2.9B
Free cash flow minus SBC	$2.3B
Gross profit	$5.2B
Income taxes	$655.2M
Investing cash flow	$-665.4M
Net borrowing	$-4.1M
Net cash flow	$883.4M
Net income	$3.3B
Operating cash flow minus SBC	$2.7B
Operating income	$3.7B
Revenue	$9.5B
Stock-based compensation	$519.4M

Metric

Value

Capital expenditures

$-374.4M

Depreciation and amortization

$143.7M

EBIT

$3.7B

EBITDA

$3.8B

EPS

$12.93

Financing cash flow

$-1.7B

Free cash flow

$2.9B

Free cash flow minus SBC

$2.3B

Gross profit

$5.2B

Income taxes

$655.2M

Investing cash flow

$-665.4M

Net borrowing

$-4.1M

Net cash flow

$883.4M

Net income

$3.3B

Operating cash flow minus SBC

$2.7B

Operating income

$3.7B

Revenue

$9.5B

Stock-based compensation

$519.4M

Metric	Value
Altman Z-Score	11.58
Book value per share	$60.24
Debt / EBITDA	0.37
Debt / equity	0.1
Debt / FCF	0.52
Goodwill	$818.8M
Interest coverage	369.14
Long-term assets	$11.2B
Long-term liabilities	$2.4B
Net cash (debt)	$8.8B
Net cash / market cap	8.86%
Net cash growth	11.07%
Net debt / EBITDA	-2.29
Net debt / equity	-0.58
Net debt / FCF	-3.07
Piotroski F-Score	5
Property, plant and equipment	$2.5B
Shareholders' equity	$15.3B
Tangible book value	$14.1B
Tangible book value per share	$55.77
Total assets	$20.7B
Total cash	$5.9B
Total debt	$1.5B
Total liabilities	$5.4B
WACC	5.72%

Metric

Value

Altman Z-Score

11.58

Book value per share

$60.24

Debt / EBITDA

0.37

Debt / equity

0.1

Debt / FCF

0.52

Goodwill

$818.8M

Interest coverage

369.14

Long-term assets

$11.2B

Long-term liabilities

$2.4B

Net cash (debt)

$8.8B

Net cash / market cap

8.86%

Net cash growth

11.07%

Net debt / EBITDA

-2.29

Net debt / equity

-0.58

Net debt / FCF

-3.07

Piotroski F-Score

Property, plant and equipment

$2.5B

Shareholders' equity

$15.3B

Tangible book value

$14.1B

Tangible book value per share

$55.77

Total assets

$20.7B

Total cash

$5.9B

Total debt

$1.5B

Total liabilities

$5.4B

WACC

5.72%

Metric	Value
Asset turnover	0.49
Current assets	$9.4B
Current liabilities	$3B
Current ratio	3.19
Inventory turnover	3.47
Net working capital	$567.8M
Quick ratio	2.54
Working capital	$6.5B
Working capital turnover	1.27

Metric

Value

Asset turnover

0.49

Current assets

$9.4B

Current liabilities

$3B

Current ratio

3.19

Inventory turnover

3.47

Net working capital

$567.8M

Quick ratio

2.54

Working capital

$6.5B

Working capital turnover

1.27

Metric	Value
Buyback yield / dilution	0.85%
Shareholder yield	0.85%

Metric

Value

Buyback yield / dilution

0.85%

Shareholder yield

0.85%

Metric	Value
150-day SMA	$481.93
1D price change	2.08%
1M price change	0.65%
1M total return	0.65%
1W price change	3.64%
1W total return	3.64%
1Y price change	25.53%
1Y return CAGR	25.55%
1Y total return	25.53%
20-day SMA	$510.05
200-day SMA	$478.71
3M price change	10.02%
3M total return	10.02%
3Y price change	48.36%
3Y return CAGR	14.05%
3Y total return	48.36%
50-day SMA	$523.17
50-day SMA vs 200-day SMA	50over200
52-week high	$577.24
52-week high date	2026-09-03
52-week low	$403.16
52-week low date	2025-11-04
5Y price change	190.92%
5Y return CAGR	23.81%
5Y total return	190.92%
6M price change	23.54%
6M total return	23.54%
All-time high	$577.24
All-time high date	2026-09-03
All-time low	$109.88
All-time low date	2014-11-10
Average true range (ATR)	$20.77
Average volume	756.3
Beta (5Y)	0.28
Change from 52-week high	-8.34%
Change from 52-week low	31.24%
Change from all-time high	-8.34%
Change from all-time low	381.54%
Change from open	4.77%
Day's gap	-2.56%
Dollar volume	$1.4M
High price	$534.99
Low price	$505.01
Monthly RSI	60.05
Open price	$505.01
Position in 52-week range	80.35%
Previous close	$518.30
Price vs 150-day SMA	9.79%
Price vs 20-day SMA	3.73%
Price vs 200-day SMA	10.53%
Price vs 50-day SMA	1.13%
Relative volume	3.57
RSI	55.69
Sharpe ratio	0.76
Sharpe ratio (3Y)	0.4
Sharpe ratio (5Y)	0.75
Sortino ratio	1.46
Sortino ratio (3Y)	0.72
Sortino ratio (5Y)	1.24
Volume	2.6K
Weekly RSI	58.74
YTD price change	16.07%
YTD total return	16.07%

Metric

Value

150-day SMA

$481.93

1D price change

2.08%

1M price change

0.65%

1M total return

0.65%

1W price change

3.64%

1W total return

3.64%

1Y price change

25.53%

1Y return CAGR

25.55%

1Y total return

25.53%

20-day SMA

$510.05

200-day SMA

$478.71

3M price change

10.02%

3M total return

10.02%

3Y price change

48.36%

3Y return CAGR

14.05%

3Y total return

48.36%

50-day SMA

$523.17

50-day SMA vs 200-day SMA

50over200

52-week high

$577.24

52-week high date

2026-09-03

52-week low

$403.16

52-week low date

2025-11-04

5Y price change

190.92%

5Y return CAGR

23.81%

5Y total return

190.92%

6M price change

23.54%

6M total return

23.54%

All-time high

$577.24

All-time high date

2026-09-03

All-time low

$109.88

All-time low date

2014-11-10

Average true range (ATR)

$20.77

Average volume

756.3

Beta (5Y)

0.28

Change from 52-week high

-8.34%

Change from 52-week low

31.24%

Change from all-time high

-8.34%

Change from all-time low

381.54%

Change from open

4.77%

Day's gap

-2.56%

Dollar volume

$1.4M

High price

$534.99

Low price

$505.01

Monthly RSI

60.05

Open price

$505.01

Position in 52-week range

80.35%

Previous close

$518.30

Price vs 150-day SMA

9.79%

Price vs 20-day SMA

3.73%

Price vs 200-day SMA

10.53%

Price vs 50-day SMA

1.13%

Relative volume

3.57

RSI

55.69

Sharpe ratio

0.76

Sharpe ratio (3Y)

0.4

Sharpe ratio (5Y)

0.75

Sortino ratio

1.46

Sortino ratio (3Y)

0.72

Sortino ratio (5Y)

1.24

Volume

2.6K

Weekly RSI

58.74

YTD price change

16.07%

YTD total return

16.07%

Metric	Value
Float	252.7M
Shares change (QoQ)	-0.43%
Shares change (YoY)	-0.85%
Shares held by insiders	0.2%
Shares held by institutions	97.11%
Short ratio	3.6 days

Metric

Value

Float

252.7M

Shares change (QoQ)

-0.43%

Shares change (YoY)

-0.85%

Shares held by insiders

0.2%

Shares held by institutions

97.11%

Short ratio

3.6 days

LON/0QZU (LON/0QZU)

Price

Financial snapshot

Fair-value bridge

Latest news · LON/0QZU

Valuation

Profitability

Balance sheet

Trading

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Sector percentile context

All LON/0QZU indicators

Profile and market data

Valuation

Profitability

Growth

Financial statements

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Deeper analysis on LON/0QZU

Frequently asked questions