LON/0QZU (LON/0QZU)

London Stock Exchange: LON/0QZU · USD

$515

-2.17 (-0.4%)· Recorded snapshot

Market cap	96.6B
Revenue (ttm)	9.5B
Net income (ttm)	3.3B
EPS (ttm)	$13.0
P/E (trailing)	29.1x
P/E (forward)	31.0x
Volume	647
Beta	0.32

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 9.5B
Net income (ttm): 3.3B
EPS (ttm): $13.0
P/E (trailing): 29.1x
P/E (forward): 31.0x
Market cap: 96.6B

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-09-13 02:00 UTC

Forward P/E31

P25 13.5P50 17.2P75 26

Trailing P/E29.1

P25 17P50 25.3P75 39.5

ROE23.5

P25 -59.1P50 -2.4P75 11.9

ROIC28.8

P25 -44P50 2.7P75 10.1

Benchmarks · 1M

S&P 500-0.9%

Nasdaq Composite-0.4%

Dow Jones Industrial Average-2.3%

Russell 2000-4.1%

All LON/0QZU indicators

Market & fundamental data

Available fields

231

Groups with data

Currency

USD

Showing 231 of 231 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Country	United States
Country code	UK
Employees	6,400
Employees Change	300%
Employees Change Percent	4.92
Enterprise value	$88B
Exchange	London Stock Exchange
Financial currency	USD
First seen	2026-05-10
Industry	Biotechnology
Isin	US92532F1003
Last refreshed	2026-09-13
Market cap	$96.6B
Price	$515
Price currency	USD
Rev Per Employee	1,482,339.48x
Sector	Healthcare
Sector PE	20.55
Sector PE Fwd	13.32
Sic	2836
Symbol	lon/0QZU
Website	https://www.vrtx.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings Yield	3.44%
EV Earnings	26.5x
EV/EBIT	24.23x
EV/EBITDA	22.06x
EV/FCF	30.75x
EV/Sales	9.45x
FCF yield	2.96%
Forward P/E	30.99x
P/B ratio	6.33x
P/E ratio	29.1x
P/S ratio	10.18x
PE Ratio10 Y	50.03x
PE Ratio3 Y	28.04x
PE Ratio5 Y	26.01x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
EBIT Margin	39%
EBITDA Margin	40.52%
FCF margin	30.75%
Gross margin	54.96%
Gross Profit	$5.2B
Gross Profit Growth	15.3%
Gross Profit Growth Q	17.23%
Gross Profit Growth3 Y	8.01%
Gross Profit Growth5 Y	11.52%
Net Income	$3.3B
Net Income Growth	21.1%
Net Income Growth Q	6.48%
Net Income Growth Qo Q	6.63%
Net Income Growth Quarters	5%
Net Income Growth Years	1%
Net Income Growth3 Y	9.4%
Net Income Growth5 Y	17.2%
Pretax Margin	41.9%
Profit Margin	35%
Profit Per Employee	$518,781
Profitable Quarters	$8
Profitable Years	1
ROA	11.93
Roa5y	14.82
ROCE	20.9
ROE	23.54
Roe5y	19
ROIC	28.8
Roic5y	37.75

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
Cagr1y	32.45%
Cagr3y	14.17%
Cagr5y	22.23%
EPS Growth	22.12
EPS Growth Q	8.02
EPS Growth Qo Q	7.21
EPS Growth Quarters	5
EPS Growth Years	1
EPS Growth3 Y	9.92
EPS Growth5 Y	17.77
FCF Growth	8.47%
FCF Growth Q	9.25%
FCF Growth Qo Q	-21.74%
FCF Growth3 Y	-0.71%
FCF Growth5 Y	16.39%
OCF Growth	11.61%
OCF Growth Q	4.87%
OCF Growth Qo Q	-21.2%
OCF Growth3 Y	1.81%
OCF Growth5 Y	15.15%
Revenue Growth	10.23x
Revenue Growth Q	12.45x
Revenue Growth Qo Q	11.62x
Revenue Growth Quarters	33x
Revenue Growth Years	11x
Revenue Growth3 Y	9.81x
Revenue Growth5 Y	13.5x

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Asset Turnover	$0.49
Assets	$20.7B
Cash	$5.9B
Current Assets	$9.3B
Current Liabilities	$2.9B
Debt	$1.5B
Debt EBITDA	$0.37
Debt Equity	$0.1
Debt FCF	$0.52
Equity	$15.3B
Interest Coverage	369.1
Liabilities	$5.4B
Long Term Assets	$11.4B
Long Term Liabilities	$2.5B
Net Cash	$8.8B
Net Cash By Market Cap	$9.1
Net Cash Growth	11.07%
Net Debt EBITDA	$-2.29
Net Debt Equity	$-0.58
Net Debt FCF	$-3.07
Tangible Book Value	$14.1B
Tangible Book Value Per Share	$55.77
WACC	5.93

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Current ratio	3.19
Inventory Turnover	3.47
Net Working Capital	$567.8M
Quick ratio	2.54
Working Capital	$6.5B
Working Capital Turnover	$1.27

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback Yield	0.85%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
1Y total return	32.43%
200-day SMA	468.1
3Y total return	48.83%
50-day SMA	510.9
50-day SMA vs 200-day SMA	50over200
5Y total return	172.77%
All Time High	577.2
All Time High Change	-10.73%
All Time High Date	2026-09-03
All Time Low	146
All Time Low Change	253.01%
All Time Low Date	2018-06-07
ATR	23.18
Beta	0.32
Ch YTD	13.04
High	524.3
High52	577.2
High52 Date	2026-09-03
High52ch	-10.73%
Low	512
Low52	375.3
Low52 Date	2025-09-24
Low52ch	37.29%
Ma50ch	0.86%
Price vs 200-day SMA	10.09%
RSI	43.29
RSI Monthly	58.32
RSI Weekly	58.66
Sharpe ratio	0.94x
Sharpe Ratio3y	0.45x
Sharpe Ratio5y	0.66x
Sortino ratio	1.83
Sortino Ratio3y	0.79
Sortino Ratio5y	1.13
Total Return	0.85%
Tr YTD	13.04
Tr1m	-2.26%
Tr1w	-6.02%
Tr3m	17.82%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	252,684,442%
Net Borrowing	-3,992,311.8
Shares Insiders	0.2%
Shares Institutions	97.13%
Shares Qo Q	-0.43%
Shares Yo Y	-0.85%
Short Ratio	3.17

Other indicators

Additional ticker metrics that do not fit the primary research groupings yet.

Metric	Value
Adjusted FCF	$2.3B
Adjusted OCF	2,716,184,060
Average Volume	715.55x
Bv Per Share	60.24
CAPEX	$-374.4M
Ch1m	-2.26
Ch1w	-6.02
Ch1y	32.43
Ch3m	17.82
Ch3y	48.83
Ch5y	172.8
Ch6m	3.37
Change	-0.42%
Change From Open	-0.37
Close	517.5
Days Gap	-0.04
Depreciation Amortization	141,135,615.3
Dollar Volume	333,392.6
Earnings Date	2026-11-02
EBIT	$3.7B
EBITDA	$3.8B
EPS	$12.95
F Score	5
FCF	$2.9B
FCF EV Yield	3.25x
Financing CF	-1,656,029,640
Fiscal Year End	December
Founded	1,989
Goodwill	804,376,896
Graham Number	180.09865
Graham Upside	-65.05
Income Tax	$655.2M
Investing CF	-665,366,360
Is Primary Listing	0
Last Earnings Date	2026-08-03
Last Report Date	2026-06-30
Lynch Fair Value	$305
Lynch Upside	-40.87
Ma150	472.9
Ma150ch	8.97%
Ma20	538.3
Ma20ch	-4.28%
Net CF	883,411,770
Next Earnings Date	2026-11-02
Open	517.2
P FCF Ratio	33.77
P FCF Ratio SBC	41.25
P OCF Ratio	29.86
P OCF Ratio SBC	35.57
Position In Range	26.92
Ppne	2,460,373,044.3
Price Date	2026-09-11
Price EBITDA	$25.13
Ptbv Ratio	6.84
Relative Volume	0.9x
Revenue	9,486,972,640x
SBC By Revenue	5.47x
Share Based Comp	519,374,670
Tax By Revenue	6.91x
Tax Rate	16.48%
Tr6m	3.37%
Volume	647
Z Score	11.58

Deeper analysis on LON/0QZU

14 sections in the full report · jump straight to what you need

Forecast

Bull, base, and bear cases with expected-return framing.

→

Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

→

Sensitivity

Cost-of-equity and terminal-growth stress table.

→

Risks

Kill scenarios, soft-pass flags, and downside catalysts.

→

Earnings

Next earnings setup and beat / inline / miss thresholds.

→

Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

→

Financials

Revenue, margins, cash flow, and balance-sheet context.

→

Peers

Relative valuation and profitability against the cohort.

→

Moat

Economic-profit evidence and competitive advantage risk.

→

Industry cycle

Sector phase, capital cycle, and secular tailwinds.

→

Scorecard

Six-factor overlay and 9-category weighted scorecard.

→

Recommendation

Final action, action steps, opportunity, and biggest risk.

→

Perspectives

Growth, value, and income investor reads.

→

Frequently asked questions

About this LON/0QZU report

Is a complete LON/0QZU research report available?

No complete published report is available for lon/0QZU (LON/0QZU) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

LON/0QZU (LON/0QZU)

London Stock Exchange: LON/0QZU · USD

$515

-2.17 (-0.4%)· Recorded snapshot

Market cap	96.6B
Revenue (ttm)	9.5B
Net income (ttm)	3.3B
EPS (ttm)	$13.0
P/E (trailing)	29.1x
P/E (forward)	31.0x
Volume	647
Beta	0.32

Market data

Price

Recent price action with selectable time range.

Financial snapshot

Revenue (ttm): 9.5B
Net income (ttm): 3.3B
EPS (ttm): $13.0
P/E (trailing): 29.1x
P/E (forward): 31.0x
Market cap: 96.6B

Calendar

Next earnings

Upcoming earnings date and setup when available.

Upcoming

DateLoading

Window—

EPS estimate—

Revenue estimate—

Sector percentile context

Refreshed 2026-09-13 02:00 UTC

Forward P/E31

P25 13.5P50 17.2P75 26

Trailing P/E29.1

P25 17P50 25.3P75 39.5

ROE23.5

P25 -59.1P50 -2.4P75 11.9

ROIC28.8

P25 -44P50 2.7P75 10.1

Benchmarks · 1M

S&P 500-0.9%

Nasdaq Composite-0.4%

Dow Jones Industrial Average-2.3%

Russell 2000-4.1%

All LON/0QZU indicators

Market & fundamental data

Available fields

231

Groups with data

Currency

USD

Showing 231 of 231 available metrics for this ticker.

Profile and market data

Ticker identity, listing, currency, market cap, and source dates.

Metric	Value
Country	United States
Country code	UK
Employees	6,400
Employees Change	300%
Employees Change Percent	4.92
Enterprise value	$88B
Exchange	London Stock Exchange
Financial currency	USD
First seen	2026-05-10
Industry	Biotechnology
Isin	US92532F1003
Last refreshed	2026-09-13
Market cap	$96.6B
Price	$515
Price currency	USD
Rev Per Employee	1,482,339.48x
Sector	Healthcare
Sector PE	20.55
Sector PE Fwd	13.32
Sic	2836
Symbol	lon/0QZU
Website	https://www.vrtx.com

Valuation

Multiples, yields, enterprise-value ratios, and valuation checks.

Metric	Value
Earnings Yield	3.44%
EV Earnings	26.5x
EV/EBIT	24.23x
EV/EBITDA	22.06x
EV/FCF	30.75x
EV/Sales	9.45x
FCF yield	2.96%
Forward P/E	30.99x
P/B ratio	6.33x
P/E ratio	29.1x
P/S ratio	10.18x
PE Ratio10 Y	50.03x
PE Ratio3 Y	28.04x
PE Ratio5 Y	26.01x

Profitability

Margins, returns on capital, cash conversion, and quality metrics.

Metric	Value
EBIT Margin	39%
EBITDA Margin	40.52%
FCF margin	30.75%
Gross margin	54.96%
Gross Profit	$5.2B
Gross Profit Growth	15.3%
Gross Profit Growth Q	17.23%
Gross Profit Growth3 Y	8.01%
Gross Profit Growth5 Y	11.52%
Net Income	$3.3B
Net Income Growth	21.1%
Net Income Growth Q	6.48%
Net Income Growth Qo Q	6.63%
Net Income Growth Quarters	5%
Net Income Growth Years	1%
Net Income Growth3 Y	9.4%
Net Income Growth5 Y	17.2%
Pretax Margin	41.9%
Profit Margin	35%
Profit Per Employee	$518,781
Profitable Quarters	$8
Profitable Years	1
ROA	11.93
Roa5y	14.82
ROCE	20.9
ROE	23.54
Roe5y	19
ROIC	28.8
Roic5y	37.75

Growth

Revenue, earnings, cash-flow, and forward growth indicators.

Metric	Value
Cagr1y	32.45%
Cagr3y	14.17%
Cagr5y	22.23%
EPS Growth	22.12
EPS Growth Q	8.02
EPS Growth Qo Q	7.21
EPS Growth Quarters	5
EPS Growth Years	1
EPS Growth3 Y	9.92
EPS Growth5 Y	17.77
FCF Growth	8.47%
FCF Growth Q	9.25%
FCF Growth Qo Q	-21.74%
FCF Growth3 Y	-0.71%
FCF Growth5 Y	16.39%
OCF Growth	11.61%
OCF Growth Q	4.87%
OCF Growth Qo Q	-21.2%
OCF Growth3 Y	1.81%
OCF Growth5 Y	15.15%
Revenue Growth	10.23x
Revenue Growth Q	12.45x
Revenue Growth Qo Q	11.62x
Revenue Growth Quarters	33x
Revenue Growth Years	11x
Revenue Growth3 Y	9.81x
Revenue Growth5 Y	13.5x

Financial strength

Debt, cash, solvency, accounting-quality, and balance-sheet signals.

Metric	Value
Asset Turnover	$0.49
Assets	$20.7B
Cash	$5.9B
Current Assets	$9.3B
Current Liabilities	$2.9B
Debt	$1.5B
Debt EBITDA	$0.37
Debt Equity	$0.1
Debt FCF	$0.52
Equity	$15.3B
Interest Coverage	369.1
Liabilities	$5.4B
Long Term Assets	$11.4B
Long Term Liabilities	$2.5B
Net Cash	$8.8B
Net Cash By Market Cap	$9.1
Net Cash Growth	11.07%
Net Debt EBITDA	$-2.29
Net Debt Equity	$-0.58
Net Debt FCF	$-3.07
Tangible Book Value	$14.1B
Tangible Book Value Per Share	$55.77
WACC	5.93

Liquidity

Current-asset coverage and working-capital efficiency metrics.

Metric	Value
Current ratio	3.19
Inventory Turnover	3.47
Net Working Capital	$567.8M
Quick ratio	2.54
Working Capital	$6.5B
Working Capital Turnover	$1.27

Dividends and buybacks

Dividend yield, payout, buybacks, and shareholder-yield indicators.

Metric	Value
Buyback Yield	0.85%

Performance and technicals

Returns, volatility, beta, momentum, RSI, and moving-average context.

Metric	Value
1Y total return	32.43%
200-day SMA	468.1
3Y total return	48.83%
50-day SMA	510.9
50-day SMA vs 200-day SMA	50over200
5Y total return	172.77%
All Time High	577.2
All Time High Change	-10.73%
All Time High Date	2026-09-03
All Time Low	146
All Time Low Change	253.01%
All Time Low Date	2018-06-07
ATR	23.18
Beta	0.32
Ch YTD	13.04
High	524.3
High52	577.2
High52 Date	2026-09-03
High52ch	-10.73%
Low	512
Low52	375.3
Low52 Date	2025-09-24
Low52ch	37.29%
Ma50ch	0.86%
Price vs 200-day SMA	10.09%
RSI	43.29
RSI Monthly	58.32
RSI Weekly	58.66
Sharpe ratio	0.94x
Sharpe Ratio3y	0.45x
Sharpe Ratio5y	0.66x
Sortino ratio	1.83
Sortino Ratio3y	0.79
Sortino Ratio5y	1.13
Total Return	0.85%
Tr YTD	13.04
Tr1m	-2.26%
Tr1w	-6.02%
Tr3m	17.82%

Ownership and float

Institutional, insider, float, short-interest, and share-count fields.

Metric	Value
Float	252,684,442%
Net Borrowing	-3,992,311.8
Shares Insiders	0.2%
Shares Institutions	97.13%
Shares Qo Q	-0.43%
Shares Yo Y	-0.85%
Short Ratio	3.17

Other indicators

Additional ticker metrics that do not fit the primary research groupings yet.

Metric	Value
Adjusted FCF	$2.3B
Adjusted OCF	2,716,184,060
Average Volume	715.55x
Bv Per Share	60.24
CAPEX	$-374.4M
Ch1m	-2.26
Ch1w	-6.02
Ch1y	32.43
Ch3m	17.82
Ch3y	48.83
Ch5y	172.8
Ch6m	3.37
Change	-0.42%
Change From Open	-0.37
Close	517.5
Days Gap	-0.04
Depreciation Amortization	141,135,615.3
Dollar Volume	333,392.6
Earnings Date	2026-11-02
EBIT	$3.7B
EBITDA	$3.8B
EPS	$12.95
F Score	5
FCF	$2.9B
FCF EV Yield	3.25x
Financing CF	-1,656,029,640
Fiscal Year End	December
Founded	1,989
Goodwill	804,376,896
Graham Number	180.09865
Graham Upside	-65.05
Income Tax	$655.2M
Investing CF	-665,366,360
Is Primary Listing	0
Last Earnings Date	2026-08-03
Last Report Date	2026-06-30
Lynch Fair Value	$305
Lynch Upside	-40.87
Ma150	472.9
Ma150ch	8.97%
Ma20	538.3
Ma20ch	-4.28%
Net CF	883,411,770
Next Earnings Date	2026-11-02
Open	517.2
P FCF Ratio	33.77
P FCF Ratio SBC	41.25
P OCF Ratio	29.86
P OCF Ratio SBC	35.57
Position In Range	26.92
Ppne	2,460,373,044.3
Price Date	2026-09-11
Price EBITDA	$25.13
Ptbv Ratio	6.84
Relative Volume	0.9x
Revenue	9,486,972,640x
SBC By Revenue	5.47x
Share Based Comp	519,374,670
Tax By Revenue	6.91x
Tax Rate	16.48%
Tr6m	3.37%
Volume	647
Z Score	11.58

Deeper analysis on LON/0QZU

14 sections in the full report · jump straight to what you need

Forecast

Bull, base, and bear cases with expected-return framing.

→

Valuation

Fair-value bridge, DCF, owner earnings, and peer multiples.

→

Sensitivity

Cost-of-equity and terminal-growth stress table.

→

Risks

Kill scenarios, soft-pass flags, and downside catalysts.

→

Earnings

Next earnings setup and beat / inline / miss thresholds.

→

Position sizing

Entry, exit, conviction, and quarterly monitoring rules.

→

Financials

Revenue, margins, cash flow, and balance-sheet context.

→

Peers

Relative valuation and profitability against the cohort.

→

Moat

Economic-profit evidence and competitive advantage risk.

→

Industry cycle

Sector phase, capital cycle, and secular tailwinds.

→

Scorecard

Six-factor overlay and 9-category weighted scorecard.

→

Recommendation

Final action, action steps, opportunity, and biggest risk.

→

Perspectives

Growth, value, and income investor reads.

→

Frequently asked questions

About this LON/0QZU report

Is a complete LON/0QZU research report available?

No complete published report is available for lon/0QZU (LON/0QZU) on this page. Market-directory data, when present, is not a substitute for a validated stock analysis.

LON/0QZU (LON/0QZU)

Price

Financial snapshot

Fair-value bridge

Latest news · LON/0QZU

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All LON/0QZU indicators

Profile and market data

Valuation

Profitability

Growth

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Other indicators

Deeper analysis on LON/0QZU

Frequently asked questions

LON/0QZU (LON/0QZU)

Price

Financial snapshot

Fair-value bridge

Latest news · LON/0QZU

Valuation

Profitability

Balance sheet

Trading

Next earnings

Sector percentile context

All LON/0QZU indicators

Profile and market data

Valuation

Profitability

Growth

Financial strength

Liquidity

Dividends and buybacks

Performance and technicals

Ownership and float

Other indicators

Deeper analysis on LON/0QZU

Frequently asked questions